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结构式 货号 产品名称 CAS号
Vazegepant hydrochloride 结构式
BCP46799 Vazegepant hydrochloride 1414976-20-7
Vazegepant hydrochloride is a highly affinity CGRP receptor antagonist (hCGRP Ki= 0.023 nM). Vazegepant is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.
NS1738 结构式
BCP46794 NS1738 501684-93-1
NS1738 is a α7 positive allosteric modulator.
CE-224535 结构式
BCP46785 CE-224535 724424-43-5
CE-224535 is a Purinergic receptor antagonist originated by Pfizer. Phase-II/III for Rheumatoid arthritis and Phase-II for Osteoarthritis were discontinued.
MK-8931 结构式
BCP46708 MK-8931 1613380-81-6
MK-8931 is a small-molecule inhibitor of BACE1 and BACE2.
Guanabenz acetate 结构式
BCP46649 醋酸胍那苄 23256-50-0
Guanabenz Acetate is the orally bioavailable, acetate salt form of guanabenz, a centrally-acting alpha-2 adrenergic receptor agonist, with anti-hypertensive and potential antineoplastic, cytoprotective and bone resorption inhibitory activities.
Vazegepant 结构式
BCP46647 Vazegepant 1337918-83-8
Vazegepant, also known as Zavegepant, BHV-3500 and BMS 742413, is a highly potent, selective and structurally unique small molecule CGRP receptor antagonist. Vazegepant is the first and only CGRP receptor antagonist for intranasal administration currently in development for the acute treatment of migraine.
Begacestat 结构式
BCP46406 贝加塞特 769169-27-9
Begacestat is a selective thiophene sulfonamide amyloid precursor protein gamma-secretase inhibitor (Aβ40,IC50=15 nM),and for the treatment of Alzheimer's disease.
Nitromazenil 结构式
BCP46523 Nitromazenil 84377-97-9
Nitromazenil is similar to Flumazenil which is an imidazodiazepine that selectively blocks the central effects of classic benzodiazepines.
Zacopride hydrochloride 结构式
BCP46391 查可必利盐酸盐 101303-98-4
Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also is a selective IK1 channel agonist.
MAO-B-IN-2 结构式
BCP46491 MAO-B-IN-2 1253978-24-3
MAO-B-IN-2 is a selective and competitive inhibitor of MAO-B and BChE with IC50 values of 0.51 and 7.00 μM, respectively.
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