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NLR

结构式 货号 产品名称 CAS号
BMS-986299 结构式
BCP44085 BMS-986299 2242952-69-6
BMS-986299 is a First-In-Class NLRP3 Innate Agonist with Potent Antitumor Activity.
Dapansutrile 结构式
BCP36209 Dapansutrile 54863-37-5
Dapansutrile is a potent, selective and orally active inhibitor of NLRP3 inflammasome. Anti-inflammatory, analgesic activity.
NOD-IN-1 结构式
BCP24808 NOD-IN-1 132819-92-2
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors, NOD1 and NOD2, with IC50 of 5.74 μM and 6.45 μM, respectively.
Troxerutin 结构式
BCP13421 曲克芦丁 7085-55-4
Troxerutin, also known as vitamin P4, is a tri-hydroxyethylated derivative of natural bioflavonoid rutins which can inhibit the production of reactive oxygen species (ROS) and depress ER stress-mediated NOD activation.
Arglabin 结构式
BCP09930 阿格拉宾 84692-91-1
Arglabin is a sesquiterpene gamma-lactone is isolated from Artemisia glabella; anticancer natural compound.
Nodinitib-1 结构式
BCP20383 Nodinitib-1 799264-47-4
Afuresertib is an orally available, ATP-competitive, pan-AKT inhibitor with Ki of 0.08, 2 and 2.6 nM against AKT1, AKT2 and AKT3, respectively.
CY09 结构式
BCP29136 CY09 1073612-91-5
CY-09 is an NLRP3 inhibitor.
MCC-950 结构式
BCP15729 MCC950 210826-40-7
MCC950(CP-456773) is a potent, selective, small-molecule inhibitor of NLRP3 with IC50 of 7.5 nM in BMDMs.
MCC950 sodium 结构式
BCP16648 MCC950 sodium 256373-96-3
MCC950 sodium is a potent, selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively.
INF-39 结构式
BCP28974 INF-39 866028-26-4
INF39 is an irreversible and noncytotoxic NLRP3 inhibitor.
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