GATA4-NKX2-5-IN-1
| CAS No. | 544681-96-1 | Cat. No. | BCP25925 |
| Name | GATA4-NKX2-5-IN-1 | ||
| Synonyms | GATA4-IN-3; | ||
| Formula | C21H23N3O2 | M. Wt | 349.43 |
| Description | GATA4-NKX2-5-IN-1 dose-dependently inhibits the GATA4–NKX2-5 transcriptional synergy with an IC50 of 3 μM. GATA4-NKX2-5-IN-1 exhibits no activity on the protein kinases involved in the regulation of GATA4 phosphorylation, and it modulates the hypertrophic agonist-induced cardiac gene expression. | ||
| Pathways | Others Pathway | ||
| Targets | Others | ||
Structure
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