PDM2
| CAS号 | 688348-25-6 | 货号 | BCP29875 |
| 中文名 | PDM2 | ||
| 英文名 | PDM2 | ||
| 中文别名 | |||
| 英文别名 | PDM-2;PDM 2; | ||
| 分子式 | C14H9Cl3 | 分子量 | 283.58 |
| 生物活性 | PDM 2 is an analog of resveratrol acting as a potent and selective aryl hydrocarbon receptor (AhR) antagonist, with a Ki of 1.2 nM. PDM 2 is inactive as a ligand for the estrogen receptor even at 100 µM. As AhR knockout mice are insensitive to the carcinogenic effects of classical AhR ligands, PDM 2 is a potential therapeutic for the treatment for dioxin and other aryl hydrocarbon poisonings. | ||
| 信号通路 | Others Pathway | ||
| 靶 点 | AhR | ||
结构式
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