MD2-IN-1
CAS号 | 111797-22-9 | 货号 | BCP29883 |
中文名 | MD2-IN-1 | ||
英文名 | MD2-IN-1 | ||
中文别名 | |||
英文别名 | MDK7229; MDK 7229; MDK 7229; | ||
分子式 | C20H22O6 | 分子量 | 358.39 |
生物活性 | MD2-IN-1 is a MD2 (Myeloid differentiation protein 2) inhibitor. MD2-IN-1 locked the LPS-induced activation of TLR4/MD2 -downstream pro-inflammatory MAPKs/NF-κB signaling pathways. In a rat model with ALI induced by intracheal LPS instillation, administration MD2-IN-1 exhibited significant protective effect against ALI, accompanied by the inhibition of TLR4/MD2 complex formation in lung tissues. | ||
信号通路 | Others Pathway | ||
靶 点 | TLR |
结构式

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