EN40
CAS号 | 2094547-67-6 | 货号 | BCP31630 |
中文名 | EN40 | ||
英文名 | EN40 | ||
中文别名 | |||
英文别名 | EN 40; EN-40;ALDH3A1 inhibitor EN40; | ||
分子式 | C13H15NO2 | 分子量 | 217.27 |
生物活性 | EN40 is a potent and selective, covalent, in vivo-active inhibitor of ALDH3A1 with IC50 of 2 uM, demonstrates no activity against ALDH1A3 and ALDH6A1 at 30 uM; also does not show any observable competition against lysine-reactive probe labeling of A549 proteomes; specifically inhibits the lung cancer cell lines expressing ALDH3A1, but not in the cell lines that do not express ALDH3A1, inhibits ALDH3A1 activity and impairs lung cancer pathogenicity in vivo. | ||
信号通路 | Protease/Metabolic Enzyme | ||
靶 点 | ALDH |
结构式

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