奥玛环素甲磺酸盐
| CAS号 | 1075240-43-5 | 货号 | BCP33017 |
| 中文名 | 奥玛环素甲磺酸盐 | ||
| 英文名 | Omadacycline tosylate | ||
| 中文别名 | 对甲苯磺酸奥玛环素; | ||
| 英文别名 | PTK 0796 tosylate;PTK-0796 tosylate;PTK0796 tosylate;Amadacyclin tosylate; | ||
| 分子式 | C36H48N4O10S | 分子量 | 728.85 |
| 生物活性 | Omadacycline, also known as PTK 0796 and Amadacyclin, is a novel first-in-class aminomethylcycline with potent activity against important skin and pneumonia pathogens, including community-acquired methicillin-resistant Staphylococcus aureus (MRSA), β-hemolytic streptococci, penicillin-resistant Streptococcus pneumoniae, Haemophilus influenzae, and Legionella. Omadacycline is active against strains expressing the two main forms of tetracycline resistance (efflux and ribosomal protection). The primary effect of omadacycline is on bacterial protein synthesis, inhibiting protein synthesis with a potency greater than that of tetracycline. The binding site for omadacycline is similar to that for tetracycline. | ||
| 信号通路 | Microbiology/Virology | ||
| 靶 点 | Antibiotic | ||
结构式
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