Vipivotide tetraxetan
| CAS号 | 1702967-37-0 | 货号 | BCP35795 |
| 中文名 | Vipivotide tetraxetan | ||
| 英文名 | Vipivotide tetraxetan | ||
| 中文别名 | |||
| 英文别名 | PSMA-617; PSMA617; PSMA 617; | ||
| 分子式 | C49H71N9O16 | 分子量 | 1042.15 |
| 生物活性 | Vipivotide tetraxetan is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer. PSMA617 possesses a small peptide, which was designed to target prostate-specific membrane antigen (PSMA). PSMA617 demonstrates high radiolytic stability for at least 72 h. PSMA617 has high inhibition potency (equilibrium dissociation constant Ki=2.34±2.94 nM on LNCaP; Ki=0.37±0.21 nM enzymatically determined). 177 Lu-PSMA-617 offers a potential additional life-prolonging treatment option for men with mCRPC. | ||
| 信号通路 | Others Pathway | ||
| 靶 点 | ADC Related | ||
结构式
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