帕罗韦德
| CAS号 | 2628280-40-8 | 货号 | BCP40653 |
| 中文名 | 帕罗韦德 | ||
| 英文名 | Paxlovid | ||
| 中文别名 | |||
| 英文别名 | PF 07321332; PF07321332;PF-07321332; | ||
| 分子式 | C23H32F3N5O4 | 分子量 | 499.53 |
| 生物活性 | PF-07321332 is an orally bioavailable 3C-like protease (3CLPRO) inhibitor. This drug is being investigated for safety, tolerability, and pharmacokinetics before moving on to studies of efficacy in the treatment or prophylaxis of COVID-19. 3CLPRO is responsible for cleaving polyproteins 1a and 1ab of SARS-CoV-2. PF-07321332 is an oral COVID-19 antiviral clinical candidate. By inhibiting the main protease, PF-07321332 prevents the virus from cleaving long protein chains into the parts it needs to reproduce itself. | ||
| 信号通路 | Microbiology/Virology | ||
| 靶 点 | SARS CoV | ||
结构式
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