他非诺喹琥珀酸盐

  • 化学数据
CAS号 106635-81-8 货号 BCP44136
中文名 他非诺喹琥珀酸盐
英文名 Tafenoquine succinate
中文别名 琥珀酸他非诺喹;
英文别名 WR 238605 Succinatee; WR-238605, WR 238605, WR238605, SB-252263-AAB; SB252263-AAB; SB 252263-AAB;
分子式 C28H34F3N3O7 分子量 581.58
  • 用途
生物活性 Tafenoquine Succinate is an 8-aminoquinoline. Tafenoquine, also known as WR-238605, is an oral active antimalaria drug that is being investigated as a potential treatment for malaria, as well as for malaria prevention. Tafenoquine Shows Activity against Trypanosoma brucei. Tafenoquine targets leishmania respiratory complex III and induces apoptosis. Tafenoquine has a long half-life of approximately 14 days and is generally safe and well tolerated, Malaria remains an important cause of global morbidity and mortality. As antimalarial drug resistance escalates, new safe and effective medications are necessary to prevent and treat malarial infection.
信号通路 Microbiology/Virology 
靶 点 Antiparasitics 

结构式

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