Amphiregulin, Human Recombinant
| CAS号 | 117147-70-3 | 货号 | BCP44759 |
| 中文名 | Amphiregulin, Human Recombinant | ||
| 英文名 | Amphiregulin, Human Recombinant | ||
| 中文别名 | |||
| 英文别名 | Amphiregulin;Keratinocyte autocrine factor; | ||
| 分子式 | 分子量 | ||
| 生物活性 | Amphiregulin is an EGF related growth factor that signals through the EGF/TGF-a receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, amphiregulin’s extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Recombinant human Amphiregulin is a 11.3 kDa glycoprotein consisting of 98 amino acid residues. | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway | ||
| 靶 点 | EGFR | ||
结构式
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