恩赛特韦富马酸盐
| CAS号 | 2757470-18-9 | 货号 | BCP46193 |
| 中文名 | 恩赛特韦富马酸盐 | ||
| 英文名 | Ensitrelvir fumarate | ||
| 中文别名 | S-217622富马酸盐; | ||
| 英文别名 | S-217622 fumarate; S 217622 fumarate; S217622 fumarate; | ||
| 分子式 | C26H21ClF3N9O6 | 分子量 | 647.96 |
| 生物活性 | Ensitrelvir, also known as S-217622, is an antiviral drug developed by Shionogi in partnership with Hokkaido University, which acts as an orally active 3C-like protease inhibitor for the treatment of COVID-19 infection. It is taken by mouth, and has been successfully tested against the recently emerged Omicron variant. It is the first orally active non-covalent, non-peptidic, SARS-CoV-2 3CL protease inhibitor (IC50=13 nM). It became the first Japanese domestic pill to treat COVID-19, third to be regulatorally approved in Japan; in February 2022. | ||
| 信号通路 | Microbiology/Virology | ||
| 靶 点 | SARS CoV | ||
结构式
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