Pertussis Toxin
| CAS No. | 70323-44-3 | Cat. No. | BCP49511 |
| Name | Pertussis Toxin | ||
| Synonyms | Pertussis toxin from Bordetella pertussis; | ||
| Formula | M. Wt | ||
| Description | Pertussis Toxin is a bacterial toxin that catalyzes ADP-ribosylation of G-proteins Gi, Go and Gt. Impairs G protein heterotrimer interaction with receptors, blocking receptor coupling. Pertussis Toxin protects against ischemic stroke in a mouse model of permanent middle cerebral artery occlusion. Pertussis Toxin inhibits microglia migration to the spinal cord and prevents dissemination of disease in an experimental autoimmune encephalomyelitis mouse model. | ||
| Pathways | Others Pathway | ||
| Targets | Others | ||
Structure
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