Soquelitinib

  • Chemical Properties
CAS No. 2226636-04-8 Cat. No. BCP49733
Name Soquelitinib
Synonyms CPI-818;CPI 818;CPI818;
Formula C25H30N4O4S2 M. Wt 514.66
  • Biological Activity
Description Soquelitinib (CPI-818) is an orally active and highly selective covalent interleukin-2-inducible kinase (ITK) inhibitor. Soquelitinib is active in six different models of T cell-mediated inflammatory and immune disease, including acute and chronic asthma, pulmonary fibrosis, systemic sclerosis (scleroderma), psoriasis, and acute graft versus host disease with Th2 cytokine product inhibition. Soquelitinib increases tumor infiltration of normal CD8+ cells that possess enhanced T effector function.
Pathways Others Pathway 
Targets Others 

Structure

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