呋喃茶碱
| CAS号 | 80288-49-9 | 货号 | BCP20952 |
| 中文名 | 呋喃茶碱 | ||
| 英文名 | Furafylline | ||
| 中文别名 | |||
| 英文别名 | Furafilina;Furafyllinum; | ||
| 分子式 | C12H12N4O3 | 分子量 | 260.25 |
| 生物活性 | Furafylline is a selective inhibitor of cytochrome P450IA2 (IC50 = 2.4 μM) and PDE (phosphodiesterase). Furafylline is a methyl xanthine derivative with an expanded duration of action in vivo than that of theophylline. Inhibition of CYP has the effect of slowing oxidative metabolism of xenobiotics, while inhibition of PDE prevents the hydrolysis of secondary messenger molecules, which in turn prolongs signal transduction and enhances its effects. | ||
| 信号通路 | Protease/Metabolic Enzyme | ||
| 靶 点 | Cytochrome P450 | ||
结构式
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