PA-824
| CAS号 | 187235-37-6 | 货号 | BCP21111 |
| 中文名 | PA-824 | ||
| 英文名 | PA-824 | ||
| 中文别名 | |||
| 英文别名 | PA824; PA 824; Pretomanid; | ||
| 分子式 | C14H12F3N3O5 | 分子量 | 359.26 |
| 生物活性 | PA-824 is an experimental anti-tuberculosis drug and one of two nitroimidazoles in phase II clinical trials to treat tuberculosis. PA-824 was tested in vitro against a broad panel of multidrug-resistant clinical isolates and was found to be highly active against all isolates (MIC<1 microg/ml). The activity of PA-824 against M. tuberculosis was also assessed grown under conditions of oxygen depletion. PA-824 showed significant activity at 2, 10, and 50 microg/ml, similar to that of metronidazole, | ||
| 信号通路 | Microbiology/Virology | ||
| 靶 点 | Antibiotic | ||
|
Genetic and Virulence Characteristics of Linezolid and Pretomanid Dual Drug-Resistant Strains Induced from Mycobacterium tuberculosis in vitro
购于瀚香生物(Biochempartner)的PA-824(CAS:187235-37-6)被引用 |
结构式
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