乙酸阿比特龙酯
| CAS号 | 154229-18-2 | 货号 | BCP02949 |
| 中文名 | 乙酸阿比特龙酯 | ||
| 英文名 | Abiraterone Acetate | ||
| 中文别名 | 阿比特隆醋酸酯; | ||
| 英文别名 | (3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol Acetate (Ester);CB 7630;CB-7630;CB7630; | ||
| 分子式 | C26H33NO2 | 分子量 | 391.55 |
| 生物活性 | Abiraterone Acetate is an orally active acetate sester form of the steroidal compound abiraterone with antiandrogen activity. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels. | ||
| 信号通路 | Protease/Metabolic Enzyme | ||
| 靶 点 | Cytochrome P450 | ||
结构式
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