甲巯咪唑
| CAS号 | 60-56-0 | 货号 | BCP02147 |
| 中文名 | 甲巯咪唑 | ||
| 英文名 | Methimazole | ||
| 中文别名 | |||
| 英文别名 | Thiamazole; Tapazole;Northyx; | ||
| 分子式 | C4H6N2S | 分子量 | 114.17 |
| 生物活性 | Methimazole(Tapazole, Northyx) is an antithyroid medicine. Methimazole is used to treat hyperthyroidism, a condition where the thyroid gland produces too much thyroid hormone. It is also used before thyroid surgery or radioactive iodine treatment.Methimazole inhibits the addition of iodine to thyroglobulin by the enzyme thyroperoxidase, a necessary step in the synthesis of triiodothyronine(T3) and thyroxine(T4). It does not inhibit the action of the sodium-dependent iodide transporter located on follicular cells’ basolateral membranes. Inhibition of this step requires competitive inhibitors such as perchlorate and thiocyanate. | ||
| 信号通路 | Others Pathway | ||
| 靶 点 | Others | ||
结构式
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