巴卡丁 III
| CAS号 | 27548-93-2 | 货号 | BCP09552 |
| 中文名 | 巴卡丁 III | ||
| 英文名 | Baccatine III | ||
| 中文别名 | 巴卡丁三; | ||
| 英文别名 | |||
| 分子式 | C31H38O11 | 分子量 | 586.63 |
| 生物活性 | Baccatin III is the precursor to paclitaxel/ taxol. Antileukaemic and antitumor agent isolated from the bark of the Pacific yew tree (Taxus breviofolia). Baccatin III binds to tubules when they are assembled in the cell and stabilizes the polymerized form of tubules so that they remain assembled even under conditions in which microtubules dissociate into tubulin subunits. Baccatin III is also an inducer of apoptosis and shows antitumor properties in vitro | ||
| 信号通路 | Cell Cycle/DNA Damage | ||
| 靶 点 | Microtubule | ||
结构式
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