托美洛韦
| CAS号 | 233254-24-5 | 货号 | BCP28085 |
| 中文名 | 托美洛韦 | ||
| 英文名 | Tomeglovir | ||
| 中文别名 | |||
| 英文别名 | BAY-38-4766; BAY 38-4766; BAY38-4766; BAY-384766; BAY 384766; BAY384766; BAY-38,4766; BAY 38,4766; BAY38,4766; | ||
| 分子式 | C23H27N3O4S | 分子量 | 441.55 |
| 生物活性 | Tomeglovir, also known as BAY-38-4766, is a non-nucleoside antiviral. Tomeglovir protects against cytomegalovirus (CMV) disease and mortality in immunocompromised guinea pigs. BAY 38-4766-resistant HCMV and MCMV strains are not cross-resistant to the nucleoside analogues ganciclovir and cidofovir or the pyrophosphate analogue foscarnet, indicating a different mode of action. Tomeglovir is highly specific for the viral as opposed to cellular functions, since UL89 is related to a bacteriophage terminase and no human equivalent exists. | ||
| 信号通路 | Microbiology/Virology | ||
| 靶 点 | CMV | ||
结构式
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