烟酰胺核苷酸

  • 化学数据
CAS号 1094-61-7 货号 BCP11124
中文名 烟酰胺核苷酸
英文名 β-Nicotinamide Mononucleotide
中文别名 Β-烟酰胺单核苷酸;β-烟酰胺单核苷酸;β-烟酰胺单核苷酸;
英文别名 Nicotinamide mononucleotide;β-nicotinamide D-ribonucleotide;Beta-Nicotinamide mononucleotide;NMN;β-NM;
分子式 C11H15N2O8P 分子量 334.22
  • 用途
生物活性 β-Nicotinamide mononucleotide is a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate.Nicotinamide Mononucleotide, also known as ("NMN" and "β-NMN") is a nucleotide derived from ribose and nicotinamide Like nicotinamide riboside, NMN is a derivative of niacin, and humans have enzymes that can use NMN to generate nicotinamide adenine dinucleotide (NADH). Because NADH is a cofactor for processes inside mitochondria, for sirtuins, and for PARP, NMN has been studied in animal models as a potential neuroprotective and anti-aging agent. Dietary supplement companies have aggressively marketed NMN products claiming those benefits, though there is no clinical study on humans published yet.
信号通路 Protease/Metabolic Enzyme 
靶 点 Nampt 

结构式

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