CH-223191
CAS号 | 301326-22-7 | 货号 | BCP12814 |
中文名 | CH-223191 | ||
英文名 | CH-223191 | ||
中文别名 | |||
英文别名 | CH223191;CH 223191; | ||
分子式 | C19H19N5O | 分子量 | 333.39 |
生物活性 | in vitro: CH-223191 preferentially inhibits the ability of some classes of AhR agonists (2,3,7,8-tetrachlorodibenzo-p-dioxin and related HAHs), but not others (PAHs, flavonoids, or indirubin), to bind to and/or activate the AhR and AhR signal transduction. CH-223191 potently inhibits TCDD-induced AhR-dependent transcription. In addition, CH-223191 blocked the binding of TCDD to AhR and inhibited TCDD-mediated nuclear translocation and DNA binding of AhR . | ||
信号通路 | Others Pathway | ||
靶 点 | AhR |
结构式

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