派姆单抗
| CAS号 | 1374853-91-4 | 货号 | BCP24244 |
| 中文名 | 派姆单抗 | ||
| 英文名 | Pembrolizumab | ||
| 中文别名 | |||
| 英文别名 | Lambrolizumab;MK-3475; | ||
| 分子式 | C6534H10004N1716O2036S46 | 分子量 | 146 kDa |
| 生物活性 | Pembrolizumab is a potent, highly selective, fully humanized immunoglobulin (Ig) G4-kappa monoclonal antibody against PD-1 with potential immune checkpoint inhibitory and antineoplastic activities. In addition to Melanoma and Lung carcinoma, pembrolizumab has also demonstrated efficacy in other advanced solid tumors and hematologic malignancies. Pembrolizumab had an acceptable side-effect profile and showed antitumor activity in patients with advanced non-small-cell lung cancer. | ||
| 信号通路 | Apoptosis Pathway | ||
| 靶 点 | PD 1/PD L1 | ||
结构式
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