Nicotinamide Riboside Chloride

  • Chemical Properties
CAS No. 23111-00-4 Cat. No. BCP20094
Name Nicotinamide Riboside Chloride
Synonyms SRT647 chloride; SRT-647 chloride; SRT 647 chloride;
Formula C11H15ClN2O5 M. Wt 290.7
  • Biological Activity
Description Nicotinamide riboside is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+. NR blocks degeneration of surgically severed dorsal root ganglion neurons ex vivo and protects against noise-induced hearing loss in living mice. Nicotinamide riboside prevents muscle, neural and melanocyte stem cell senescence. Increased muscular regeneration in mice has been observed after treatment with nicotinamide riboside, leading to speculation that it might improve regeneration of organs such as the liver, kidney, and heart. Nicotinamide riboside also lowers blood glucose and fatty liver in prediabetic and type 2 diabetic models while preventing the development of diabetic peripheral neuropathy. Note: Nicotinamide Riboside chloride is a α/β mixture

Structure

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