Atabecestat

  • Chemical Properties
CAS No. 1200493-78-2 Cat. No. BCP25878
Name Atabecestat
Synonyms JNJ-54861911; JNJ54861911; JNJ 54861911; RSC-385896; RSC 385896; RSC385896;
Formula C18H14FN5OS M. Wt 367.4
  • Biological Activity
Description Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction. Atabecestat (JNJ-54861911) is tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimer's Disease treatment.
Pathways Neuro Signaling Pathway 
Targets Beta secretase 

Structure

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