AX-024 hydrochloride
| CAS号 | 1704801-24-0 | 货号 | BCP30050 |
| 中文名 | AX-024 hydrochloride | ||
| 英文名 | AX-024 hydrochloride | ||
| 中文别名 | |||
| 英文别名 | AX-024 HCl;AX 024 HCl;AX024 HCl;AX024 hydrochloride ;AX 024 hydrochloride; | ||
| 分子式 | C21H23ClFNO2 | 分子量 | 375.86 |
| 生物活性 | AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.AX-024 is an orally available inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation (IC50 value 1 nM). Inhibiting an immediate TCR signal has promise for treating a broad spectrum of human T cell-mediated autoimmune and inflammatory diseases. | ||
| 信号通路 | Apoptosis Pathway Others Pathway | ||
| 靶 点 | Interleukin Related TNF Receptor | ||
结构式
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