KHS101
| CAS号 | 1262770-73-9 | 货号 | BCP30177 |
| 中文名 | KHS101 | ||
| 英文名 | KHS101 | ||
| 中文别名 | |||
| 英文别名 | KHS 101;KHS-101; | ||
| 分子式 | C18H21N5S | 分子量 | 339.46 |
| 生物活性 | KHS-101 (KHS101) is a small molecule that selectively induces a neuronal differentiation phenotype, induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3 (EC50=1 uM); works indirectly on HIF complex formation by destabilizing both TACC3 and the HIF component HIF-1α, decreases TACC3 levels in cells and regulates HIF gene expression; significantly increases neuronal differentiation in rats in vivo. | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
| 靶 点 | HIF | ||
结构式
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