Pristinamycin IA

  • Chemical Properties
CAS No. 3131-03-1 Cat. No. BCP31526
Name Pristinamycin IA
Synonyms Ostreogrycin B;Mikamycin B;Vernamycin BA;Mikamycin IA;Streptogramin B;
Formula C45H54N8O10 M. Wt 866.96
  • Biological Activity
Description Pristinamycin IA is a macrolide antibiotic that inhibits the growth of Clostridium, Peptostreptococcus, and Propionibacterium bacterial species. Streptogramin B inhibits protein synthesis by interacting with the 50S ribosome. Resistance to streptogramin B is conferred by erythromycin ribosome methylation (erm) genes, which code for methylases that methylate the 50S ribosome, interfering with streptogramin B binding.
Pathways Microbiology/Virology 
Targets Antibiotic 

Structure

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