Gusacitinib盐酸盐
| CAS号 | GusacitinibHCl | 货号 | BCP31676 |
| 中文名 | Gusacitinib盐酸盐 | ||
| 英文名 | Gusacitinib HCl | ||
| 中文别名 | ASN002盐酸盐; | ||
| 英文别名 | ASN002 hydrochloride; ASN002 HCl;ASN-002 HCl;ASN 002 HCl; | ||
| 分子式 | C24H29ClN8O2 | 分子量 | 497.00 |
| 生物活性 | Gusacitinib is a potent dual inhibitor of SYK/JAK kinases. ASN002 showed strong antitumor activity in both hematological and solid tumor xenograft models. ASN002 strongly suppressed the SYK and JAK family kinase signaling pathways as measured in pLAT and pSTAT assays, respectively. When profiled in a panel of 178 cell lines, ASN002 showed strong anti-proliferative activity in many lymphoid/leukemia cell lines, including SU-DHL-6, SU-DHL-4, OCI-LY10, H929 and Pfeiffer. | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway Wnt/Stem Cell Epigenetics | ||
| 靶 点 | JAK Syk | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！