PF-03463275 HCl

  • Chemical Properties
CAS No. 1173177-11-1 Cat. No. BCP32015
Name PF-03463275 HCl
Synonyms PF-03463275; PF03463275; PF 03463275; PF-3463275; PF3463275; PF 3463275;
Formula C19H23Cl2FN4O M. Wt 413.3
  • Biological Activity
Description PF-03463275 (PF 3463275) ia an orally bioavailable, centrally penetrant, potent, reversible, selective, and competitive inhibitor of the human GlyT1 transporter with Ki of 13 nM; shows no significant affinity for GlyT2 (Ki >1 mM); is under investigation for the treatment of schizophrenia.
Pathways Ion Channel/Membrane Transporter 
Targets GlyT 

Structure

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