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Ion Channel/Membrane Transporter

Chemical Structure Cat. No. Product Name CAS No.
Verinurad Chemical Structure
 BCP17058 Verinurad 1352792-74-5
Verinurad is an urate transporter inhibitor with EC50 value of 0.05 μM.
Nicainoprol Chemical Structure
 BCP30068 Nicainoprol 76252-06-7
Nicainoprol is a fast-sodium-channel blocking drug, which is a potent antiarrhythmic agent.
PST2286 Chemical Structure
 BCP08064 PST2286 26629-41-4
PST2286, also known as 17-Hydroxydigitoxigenin, is a rostafuroxin metabolite.
Glybenclamide Chemical Structure
 BCP05327 Glybenclamide 10238-21-8
Glibenclamide is a sulfonylurea compound that modulates insulin production.
SAGE-217 Chemical Structure
 BCP30027 SAGE-217 1632051-40-1
SAGE-217 is a potent GABAA receptor agonist with EC50s of 296 and 163 nM for α1β2γ2 and α4β3δ GABAA receptors, respectively.
Eliprodil Chemical Structure
 BCP23813 Eliprodil 119431-25-3
Eliprodil(SL-820715) is a non-competitive NR2B-NMDA receptor antagonist(IC50=1 uM), less potent for NR2A- and NR2C-containing receptors(IC50> 100 uM).
Icilin Chemical Structure
 BCP27818 Icilin 36945-98-9
Icilin(AG 3-5) is a synthetic super-agonist of TRPM8 ion channel.
HC-070 Chemical Structure
 BCP29966 HC-070 1628291-95-1
HC-070 is a potent inhibitor of TRPC4 and TRPC5, leading to anxiolytic and antidepressant effects in mice.
Gefapixant Chemical Structure
 BCP26079 Gefapixant 1015787-98-0
Gefapixant is an orally active P2X3 receptor (P2X3R) antagonist with IC 50s of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors.
Tenapanor Chemical Structure
 BCP24892 Tenapanor 1234423-95-0
Tenapanor is an inhibitor of the Na+/H+ exchanger NHE3 with IC50 values of 5 and 10 nM against human and Rat NHE3, respectively.
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