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Ion Channel/Membrane Transporter

Chemical Structure Cat. No. Product Name CAS No.
Isourolithin B Chemical Structure
BCP36684 Isourolithin B 855255-55-9
Urolithin C Chemical Structure
BCP36683 Urolithin C 165393-06-6
Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion.
Clomethiazole Chemical Structure
BCP36337 Clomethiazole 533-45-9
Chlormethiazole is an potent and orally active GABAA agonist. Chlormethiazole inhibits cytochrome P450 isoforms: CYP2A6 and CYP2E1 in human liver microsomes. Chlormethiazole is an anticonvulsant agent and has the potential for treating convulsive status epilepticus.
Spermidine trihydrochloride Chemical Structure
BCP36231 Spermidine trihydrochloride 334-50-9 
Spermidine trihydrochloride is a polyamine that binds to NMDA receptor.
GSK2193874 Chemical Structure
BCP36070 GSK2193874 1336960-13-4
GSK2193874 is an orally active, potent, and selective TRPV4 antagonist with IC50s of 2 nM and 40 nM for rTRPV4 and hTRPV4.
Golexanolone Chemical Structure
BCP36048 Golexanolone 2089238-18-4
Golexanolone is a GABA-A receptor modulating steroid antagonist that selectively antagonizes the enhanced activation of GABAA receptors by neurosteroids such as allopregnanolone and THDOC.
Leptomycin B Chemical Structure
BCP35974 Leptomycin B 87081-35-4
Leptomycin B is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle.
Licarbazepine Chemical Structure
BCP35919 Licarbazepine 29331-92-8
Licarbazepine is a voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects that is related to oxcarbazepine. It is an active metabolite of oxcarbazepine. In addition, an isomer of licarbazepine, eslicarbazepine ((S)-(+)-licarbazepine), is an active metabolite of eslicarbazepine acetate. Oxcarbazepine and eslicarbazepine acetate are inactive on their own, and behave instead as prodrugs to licarbazepine and eslicarbazepine, respectively, to produce their therapeutic effects.
Elexacaftor R enantiomer Chemical Structure
BCP35907 Elexacaftor R enantiomer 2229860-99-3
Elexacaftor (VX-445,) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR). Elexacaftor (VX-445) facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface.
Licogliflozin Chemical Structure
BCP35901 Licogliflozin 1291094-73-9
Licogliflozin is a sodium glucose cotransporter (SGLT1 and SGLT2) inhibitor.
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