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Ion Channel/Membrane Transporter

Chemical Structure Cat. No. Product Name CAS No.
Lu AF27139 Chemical Structure
 BCP44190 Lu AF27139 2097117-06-9
Lu AF27139, a novel rodent-active and CNS-penetrant P2X7 receptor antagonist.
Hypotaurine Chemical Structure
 BCP44138 Hypotaurine 300-84-5
Hypotaurine is an aminosulfinic acid comprising ethylamine having the sulfo group at the 2-position.
JNJ-54166060 Chemical Structure
 BCP44118 JNJ-54166060 1627900-42-8
JNJ-54166060 is a potent P2X7 antagonist.
Tulrampator Chemical Structure
 BCP44153 Tulrampator 1038984-31-4
Tulrampator, also known as S-47445 and CX-1632, is a positive allosteric modulator (PAM) of the AMPA receptor (AMPAR), an ionotropic glutamate receptor.
Rohitukine Chemical Structure
 BCP44052 Rohitukine 71294-60-5
Rohitukine is an anti-cancer agent. It acts through gastrin antagonism and H(+) K (+)-ATPase inhibition to modulate apoptosis pathways. Rohitukine ia an antidyslipidemic, antiadipogenic, gastroprotective, antifertility, and antileishmanial compound.
Dimiracetam Chemical Structure
 BCP44036 Dimiracetam 126100-97-8
Dimiracetam is a NMDA-receptor antagonist potentially for the treatment of neuropathic pain
Terfenadine Chemical Structure
 BCP43974 Terfenadine 50679-08-8
Terfenadine is a potent open-channel blocker of hERG with a mean IC50 of 204 nM.
Caroverine Chemical Structure
 BCP43855 Caroverine 23465-76-1
Caroverine is a potential chemotherapeutical agent in HNSCC cell lines.
Caroverine hydrochloride Chemical Structure
 BCP43849 Caroverine hydrochloride 55750-05-5
Caroverine hydrochloride is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. Caroverine hydrochloride is also an antioxidant and calcium-blocking agent that exhibits vasorelaxant action. Caroverine hydrochloride can be used for the research of inner ear tinnitus.
ML-SA5 Chemical Structure
 BCP43794 ML-SA5 2418670-70-7
ML-SA5 is a novel mucolipin 1 (ML1) agonist, inducing lysosomal Ca2+ release, ameliorating muscular dystrophies and activating TFEB to correct lysosomal insufficiency in mdx mice.
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