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Ion Channel/Membrane Transporter

Chemical Structure Cat. No. Product Name CAS No.
ASP7663 Chemical Structure
 BCP33952 ASP7663 1190217-35-6
ASP7663 has been found to be a TRPA1 activator and could show abdominal analgesic activities.
MCHr1 antagonist 2 Chemical Structure
 BCP33948 MCHr1 antagonist 2 863115-70-2
MCH-R1 antagonist 22 is a novel potent antagonist of melanin concentrating hormone receptor 1 (MCH-R1).
Zamicastat Chemical Structure
 BCP33811 Zamicastat 1080028-80-3
Zamicastat is a dopamine β-hydroxylase (DBH) inhibitor that could cross the blood-brain barrier (BBB) and cause central as well as peripheral effects. Zamicastat is also a concentration-dependent dual P-gp and BCRP inhibitor with IC50 values of 73.8 μM and 17.0 μM, respectively. Reduces high blood pressure.
Encequidar mesylate Chemical Structure
 BCP33772 Encequidar mesylate 849675-87-2
Encequidar mesylate (HM30181 mesylate) is a competitive and potent P-glycoprotein inhibitor.
MRS 2365 Chemical Structure
 BCP33766 MRS 2365 436847-09-5
MRS2365 is a highly potent, selective P2Y1 receptor agonist (EC50 = 0.4 nM). Displays no activity at P2Y12 receptors and only very low agonist activity at P2Y13 receptors (at concentrations up to 1 μM). Increases the upregulation of NTPDase1 by ATPγS.
PF-04745637 Chemical Structure
 BCP33691 PF-04745637 1917294-46-2
PF-04745637 is a TRPV1 antagonist.
Adenosine triphosphate disodium Chemical Structure
 BCP33634 Adenosine triphosphate disodium 987-65-5
ATP disodium salt is a disodium salt form of adenosine-triphosphate which is a multifunctional nucleoside triphosphate.
Oxcarbazepine Chemical Structure
 BCP33398 Oxcarbazepine 28721-07-5
Oxcarbazepine is a sodium channel protein inhibitor.
Efonidipine hydrochloride ethanolate Chemical Structure
 BCP33396 Efonidipine hydrochloride ethanolate 111011-76-8
Efonidipine hydrochloride monoethanolate is a dual T-type and L-type calcium channel blocker (CCB).The hydrochloride monoethanolate salt form of Efonidipine which has been launched for hypertension and discontinued for cerebrovascular disorders.
nAChR agonist 1 Chemical Structure
 BCP33344 nAChR agonist 1 1394371-75-5
nAChR agonist 1 is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR).
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