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Ion Channel/Membrane Transporter

Chemical Structure Cat. No. Product Name CAS No.
FDL169 Chemical Structure
 BCP30546 FDL169 1628416-28-3
FDL169 is an experimental therapy for cystic fibrosis (CF) that is being developed by Flatley Discovery Lab.
(-)-MK 801 Maleate Chemical Structure
 BCP28727 (-)-MK 801 Maleate 121917-57-5
(-)-MK 801 Maleate is the enantiomer of (+)-MK-801. (+)-MK 801 Maleate is a potent, selective and non-competitive NMDA receptor antagonist.
Talinolol Chemical Structure
 BCP30483 Talinolol 57460-41-0
Talinolol is a beta(1)-adrenergic receptor antagonist and a probe drug for P-glycoprotein (P-gp) activity in humans.
Lidocaine hydrochloride Chemical Structure
 BCP30473 Lidocaine hydrochloride 73-78-9
Lidocaine hydrochloride is a local anesthetic and cardiac depressant used as an antiarrhythmia agent. Originally developed as a local anesthetic, it has properties as a class IB antiarrhythmic, a long-acting membrane stabilizing agent used against ventricular arrhythmia. Its actions are more intense and its effects more prolonged than those of procaine but its duration of action is shorter than that of bupivacine or prilocaine.
Ganaxolone Chemical Structure
 BCP30445 Ganaxolone 38398-32-2
Ganaxolone, also known as CCD 1042 and C1042, is a CNS-selective GABAA modulator that acts on well-characterized targets in the brain known to have anxiolytic and anticonvulsant effects. Ganaxolone protects against seizures in diverse animal models, including the pentylenetetrazol, 6 Hz and amygdala kindling models. Ganaxolone is a positive allosteric modulator of the action of the GABAA receptor and, unlike benzodiazepines, there does not appear to be tolerance to the anticonvulsant effects of ganaxolone.
Atracurium besylate Chemical Structure
 BCP22909 Atracurium besylate 64228-81-5
Atracurium Besylate is a neuromuscular blocking agent with ED95 of 0.2 mg/kg.
UR 1102 Chemical Structure
 BCP30414 UR 1102 1198153-15-9
UR 1102 is an inhibitor of the renal urate transporter URAT1. UR 1102 effectively increases the fractional excretion of urinary uric acid, and reduces plasma uric acid. It is promisingly used as a therapeutic for gout or hyperuricemia with an enhanced pharmacokinetic profile.
(S)-B-973B Chemical Structure
 BCP30366 (S)-B-973B 2244989-34-0
(S)-B-973B is a potent allosteric agonism and positive allosteric modulation (ago-PAM) for α7 nAChR, with antinociceptive activity.
Gaboxadol Hydrochloride Chemical Structure
 BCP16610 Gaboxadol Hydrochloride 85118-33-8
Gaboxadol is a GABA agonist.
Aminooxyacetic acid Chemical Structure
 BCP30347 Aminooxyacetic acid 645-88-5
Aminooxyacetic acid is a compound that inhibits 4-aminobutyrate aminotransferase (GABA-T) activity in vitro and in vivo, leading to less gamma-aminobutyric acid (GABA) being broken down.
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