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PI3K/Akt/mTOR

Chemical Structure Cat. No. Product Name CAS No.
GSK-3 Inhibitor XV Chemical Structure
BCP42764 GSK-3 Inhibitor XV 936112-69-5
GSK3 inhibitor XV is a racemic mixture of (R)-GSK3 inhibitor XV and (S)-GSK3 inhibitor XV.
BC1618 Chemical Structure
BCP42670 BC1618 2222094-18-8
BC1618 is a novel Fbxo48 inhibitor and prevent pAmpkα degradation with MEC (minimal efficacious concentration) of 0.6 μM.
Parsaclisib hydrochloride Chemical Structure
BCP42656 Parsaclisib hydrochloride 1995889-48-9
Parsaclisib, also known as INCB050465, is a novel PI3Kδ inhibitor which synergizes with PIM protein kinase inhibition to cause tumor regression in a model of DLBCL.
PI4KIII beta inhibitor 9 Chemical Structure
BCP41897 PI4KIII beta inhibitor 9 1429624-84-9
PI4KIIIbeta-IN-9 is a potent PI4KIIIβ inhibitor. It also inhibits PI3Kδ and PI3Kγ.
PI4KIII beta inhibitor 10 Chemical Structure
BCP41882 PI4KIII beta inhibitor 10 1881233-39-1
PI4KIIIbeta-IN-10 is a novel potent PI4KIIIβ inhibitor (IC50 3.6 nM).
PIK-108 Chemical Structure
BCP41853 PIK-108 901398-68-3
PIK-108 is an allosteric inhibitor of the lipid modifying kinases, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunits β and δ (PI3Kβ/δ).
TAS-117 Chemical Structure
BCP41128 TAS-117 1402602-94-1
TAS-117 is a PKB/Akt inhibitor potentially for the treatment of solid tumors.
PF-06679142 Chemical Structure
BCP40393 PF-06679142 1467059-66-0
PF-06679142 is a potent AMPK activator.
SRX3207 Chemical Structure
BCP40266 SRX3207 2254693-15-5
SRX3207 is an orally active dual inhibitor of Syk-PI3K with IC50 of 39.9 nM, 31200 nM, 3070 nM, 3070 nM, 244 nM, 388 nM, 9790 nM for Syk, Zap70, BRD41, BRD42, PI3K alpha, PI3K delta, PI3K gamma, respectively.
IPI-3063 Chemical Structure
BCP39855 IPI-3063 1425043-73-7
IPI-3063 is a potent and selective phosphoinoside-3-kinase (PI3K) p110δ inhibitor. IPI-3063 was shown to inhibit mouse B cell proliferation, survival, and plasmablast differentiation, and also inhibit human B cell proliferation in vitro.
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