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PI3K/Akt/mTOR

Chemical Structure Cat. No. Product Name CAS No.
Ipatasertib dihydrochloride Chemical Structure
BCP23821 Ipatasertib dihydrochloride 1396257-94-5
Ipatasertib dihydrochloride is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5/18/8 nM, 620-fold selectivity over PKA.
Recilisib Chemical Structure
BCP31296 Recilisib 334969-03-8
Recilisib is a radioprotectant, which can activate AKT, PI3K activities in cells.
Pterosin B Chemical Structure
BCP09994 Pterosin B 34175-96-7
Pterosin B is isolated and purified from the aerial parts of Pteris semipinnata.
VP3.15 dihydrobromide Chemical Structure
BCP31222 VP3.15 dihydrobromide 1281681-33-1
VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively.
VP3.15 Chemical Structure
BCP31223 VP3.15 1281681-54-6
VP3.15 is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively.
SL 0101-1 Chemical Structure
BCP21457 SL 0101-1 77307-50-7
SL0101 is a highly specific RSK inhibitor. SL0101 showed improved in vitro biological stability while maintaining specificity for RSK. These results should facilitate the development of RSK inhibitors derived from SL0101 as anticancer agents.
NVP-QAV-572 Chemical Structure
BCP27906 NVP-QAV-572 957209-68-6
NVP-QAV-572 is a potent PI3K kianse inhibitor.
Sonolisib Chemical Structure
BCP27666 Sonolisib 502632-66-8
Sonolisib is an improved Wortmannin analogue, is an oral, irreversible, and pan-isoform inhibitor of PI3K (IC50=0.1 nM (p110α), 1.0 nM (p120γ), 2.9 nM (p110δ)). Antitumor activity.
D-106669 Chemical Structure
BCP27662 D-106669 938444-93-0
D 106669 is a potent and selective PI3K inhibitor.
D-87503 Chemical Structure
BCP27634 D-87503 800394-83-6
D-87503 is a dual extracellular signaling-related kinase (ERK)/PI3K inhibitor.
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