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PI3K/Akt/mTOR

Chemical Structure Cat. No. Product Name CAS No.
GDC-0077 Chemical Structure
BCP25972 GDC-0077 2060571-02-8
GDC-0077 is a potent and selective PI3K inhibitor. GDC-0077 blocks an enzyme involved in cancer growth called PI3K.
SAR-260301 Chemical Structure
BCP13808 SAR-260301 1260612-13-2
SAR260301 is potent and selective Class I phosphatidylinositol-3-kinase (PI3K)β specific inhibitor with an IC50 of 52 nM for this isoform.
Akt-I-2 HCl Chemical Structure
BCP18315 Akt-I-2 HCl 473382-50-2
Akt-I-1,2 is a selective Akt1 and Akt2 inhibitor.
BAY-1125976 Chemical Structure
BCP20659 BAY-1125976 1402608-02-9
BAY1125976 is a selective allosteric Akt1/2 inhibitor; inhibits Akt1 and Akt2 activity with IC50 values of 5.2 nM and 18 nM at 10 μM ATP, respectively.
ATR inhibitor 1 Chemical Structure
BCP23596 ATR inhibitor 1 1613200-51-3
Carnosol Chemical Structure
BCP20030 Carnosol 5957-80-2
Carnosol is a potent Ribosomal S6 Kinase (RSK2) inhibitor that could be useful for treating gastric cancer, with an IC50 of ~5.5 μM.
UCN-01 Chemical Structure
BCP14345 UCN-01 112953-11-4
UCN-01 (7-hydroxystaurosporine) acts as an inhibitor against many phosphokinases, such as the serine/threonine kinase AKT, calcium-dependent protein kinase C, and cyclin-dependent kinases.
GSK-F1 Chemical Structure
BCP29575 GSK-F1 1402345-92-9
GSK-F1 is a novel potent inhibitor of PI4KA.
GSK-A1 Chemical Structure
BCP28055 GSK-A1 1416334-69-4
GSK-A1 is a novel potent inhibitor of PI4KA.
UCB9608 Chemical Structure
BCP29663 UCB9608 1616413-96-7
UCB9608 is a Potent, Orally Bioavailable PI4KIIIβ Inhibitor.
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