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P2 Receptor

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P2 Receptor

Chemical Structure Cat. No. Product Name CAS No.
JNJ-54175446 Chemical Structure
 BCP31541 JNJ-54175446 1627902-21-9
JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively.
Vicagrel Chemical Structure
 BCP24464 Vicagrel 1314081-53-2
Vicagrel, an acetate derivative of Clopidogrel, is a P2Y12 platelet inhibitor potentially for the treatment of thrombosis.
GW791343 trihydrochloride Chemical Structure
 BCP23425 GW791343 trihydrochloride 309712-55-8
GW791343 3HCl is a HCl salt form of GW791343, which is a non-competitive allosteric modulator of human P2X7 receptor inhibitor with pIC50 of 7.
Uridine-5'-triphosphoric acid trisodium salt Chemical Structure
 BCP30809 Uridine-5'-triphosphoric acid trisodium salt 19817-92-6
Uridine 5’-Triphosphate Trisodium Salt is a polyphosphate analogue of uridine that is used in the synthesis of agonists at the G-protein-coupled P2Y receptors.
Uridine-5'-diphosphate disodium salt Chemical Structure
 BCP30808 Uridine-5'-diphosphate disodium salt 27821-45-0
UDP disodium salt is an endogenous P2Y receptor agonist which preferentially activates P2Y6.
Clopidogrel Besylate Chemical Structure
 BCP13469 Clopidogrel Besylate 744256-69-7
Clopidogrel besylate is a ticlopidine analog and platelet purinergic P2Y receptor antagonist that inhibits adenosine diphosphate-mediated PLATELET AGGREGATION.
Clopidogrel thiolactone Chemical Structure
 BCP15749 Clopidogrel thiolactone 1147350-75-1
2-Oxoclopidogrel is a metabolite of Clopidogrel.
Gefapixant Chemical Structure
 BCP26079 Gefapixant 1015787-98-0
Gefapixant is an orally active P2X3 receptor (P2X3R) antagonist with IC 50s of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors.
RO-3 Chemical Structure
 BCP18267 RO-3 1026582-88-6
RO-3 is a selective P2X3 and P2X2/3 antagonist.
Cangrelor tetrasodium Chemical Structure
 BCP15965 Cangrelor tetrasodium 163706-36-3
Cangrelor is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhibition of ADP-induced platelet aggregate.
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