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P2 Receptor

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P2 Receptor

Chemical Structure Cat. No. Product Name CAS No.
Diquafosol Chemical Structure
 BCP32158 Diquafosol 59985-21-6
Diquafosol is involved in pyrimidine metabolism. It is a precurser for UTP. UTP is produced from P1, P4-Bis(5'-uridyl) tetraphosphate by the action of bis(5'-nucleosidyl)-tetraphosphatase.
BzATP triethylammonium salt Chemical Structure
 BCP32055 BzATP triethylammonium salt 112898-15-4
BzATP triethylammonium salt is a prototypic P2X7 receptor agonist that exhibits 5 - 10 fold greater potency than ATP (EC50 = 0.7 μM in HEK 293 cells; EC50 values are 3.6 and 285 μM for rat and mouse receptors respectively). Exhibits partial agonist activity at P2X1 (pEC50 = 8.7) and P2Y1 receptors and can be used as a photoaffinity label for ATPase.
BzATP Chemical Structure
 BCP32054 BzATP 81790-82-1
BzATP is a prototypic P2X7 receptor agonist (EC50 values are 3.6, 7 and 285 μM for rat, human and mouse receptors respectively). Exhibits 5 - 10 fold greater potency than ATP. Exhibits partial agonist activity at P2X1 (pEC50 = 8.7) and P2Y1 receptors and can be used as a photoaffinity label for ATPase.
JNJ-54175446 Chemical Structure
 BCP31541 JNJ-54175446 1627902-21-9
JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively.
Vicagrel Chemical Structure
 BCP24464 Vicagrel 1314081-53-2
Vicagrel, an acetate derivative of Clopidogrel, is a P2Y12 platelet inhibitor potentially for the treatment of thrombosis.
GW791343 trihydrochloride Chemical Structure
 BCP23425 GW791343 trihydrochloride 309712-55-8
GW791343 3HCl is a HCl salt form of GW791343, which is a non-competitive allosteric modulator of human P2X7 receptor inhibitor with pIC50 of 7.
Uridine-5'-triphosphoric acid trisodium salt Chemical Structure
 BCP30809 Uridine-5'-triphosphoric acid trisodium salt 19817-92-6
Uridine 5’-Triphosphate Trisodium Salt is a polyphosphate analogue of uridine that is used in the synthesis of agonists at the G-protein-coupled P2Y receptors.
Uridine-5'-diphosphate disodium salt Chemical Structure
 BCP30808 Uridine-5'-diphosphate disodium salt 27821-45-0
UDP disodium salt is an endogenous P2Y receptor agonist which preferentially activates P2Y6.
Clopidogrel Besylate Chemical Structure
 BCP13469 Clopidogrel Besylate 744256-69-7
Clopidogrel besylate is a ticlopidine analog and platelet purinergic P2Y receptor antagonist that inhibits adenosine diphosphate-mediated PLATELET AGGREGATION.
Clopidogrel thiolactone Chemical Structure
 BCP15749 Clopidogrel thiolactone 1147350-75-1
2-Oxoclopidogrel is a metabolite of Clopidogrel.
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