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P2 Receptor

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P2 Receptor

Chemical Structure Cat. No. Product Name CAS No.
A 438079 Hydrochloride Chemical Structure
 BCP34027 A 438079 Hydrochloride 899507-36-9
A 438079 is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9.
MRS 2365 Chemical Structure
 BCP33766 MRS 2365 436847-09-5
MRS2365 is a highly potent, selective P2Y1 receptor agonist (EC50 = 0.4 nM). Displays no activity at P2Y12 receptors and only very low agonist activity at P2Y13 receptors (at concentrations up to 1 μM). Increases the upregulation of NTPDase1 by ATPγS.
Adenosine triphosphate disodium Chemical Structure
 BCP33634 Adenosine triphosphate disodium 987-65-5
ATP disodium salt is a disodium salt form of adenosine-triphosphate which is a multifunctional nucleoside triphosphate.
AZD-9056 hydrochloride Chemical Structure
 BCP25556 AZD-9056 hydrochloride 345303-91-5
AZD-9056 hydrochloride is a novel, potent, selective, orally bioavailable p2x7 receptor antagonist.
Diquafosol tetrasodium Chemical Structure
 BCP25932 Diquafosol tetrasodium 211427-08-6
Diquafosol tetrasodium is a P2Y2 receptor agonist that stimulates fluid and mucin secretion on the ocular surface, as a topical treatment of dry eye disease.
Diquafosol Chemical Structure
 BCP32158 Diquafosol 59985-21-6
Diquafosol is involved in pyrimidine metabolism. It is a precurser for UTP. UTP is produced from P1, P4-Bis(5'-uridyl) tetraphosphate by the action of bis(5'-nucleosidyl)-tetraphosphatase.
BzATP triethylammonium salt Chemical Structure
 BCP32055 BzATP triethylammonium salt 112898-15-4
BzATP triethylammonium salt is a prototypic P2X7 receptor agonist that exhibits 5 - 10 fold greater potency than ATP (EC50 = 0.7 μM in HEK 293 cells; EC50 values are 3.6 and 285 μM for rat and mouse receptors respectively). Exhibits partial agonist activity at P2X1 (pEC50 = 8.7) and P2Y1 receptors and can be used as a photoaffinity label for ATPase.
BzATP Chemical Structure
 BCP32054 BzATP 81790-82-1
BzATP is a prototypic P2X7 receptor agonist (EC50 values are 3.6, 7 and 285 μM for rat, human and mouse receptors respectively). Exhibits 5 - 10 fold greater potency than ATP. Exhibits partial agonist activity at P2X1 (pEC50 = 8.7) and P2Y1 receptors and can be used as a photoaffinity label for ATPase.
JNJ-54175446 Chemical Structure
 BCP31541 JNJ-54175446 1627902-21-9
JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively.
Vicagrel Chemical Structure
 BCP24464 Vicagrel 1314081-53-2
Vicagrel, an acetate derivative of Clopidogrel, is a P2Y12 platelet inhibitor potentially for the treatment of thrombosis.
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