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P2 Receptor

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P2 Receptor

Chemical Structure Cat. No. Product Name CAS No.
Lu AF27139 Chemical Structure
 BCP44190 Lu AF27139 2097117-06-9
Lu AF27139, a novel rodent-active and CNS-penetrant P2X7 receptor antagonist.
JNJ-54166060 Chemical Structure
 BCP44118 JNJ-54166060 1627900-42-8
JNJ-54166060 is a potent P2X7 antagonist.
AZ10606120 dihydrochloride Chemical Structure
 BCP43716 AZ10606120 dihydrochloride 607378-18-7
AZ10606120 dihydrochloride is a potent, specific P2X7 receptor antagonist that strongly inhibits tumor growth in B16-inoculated C57Bl/6 mice.
2-Methylthioadenosine diphosphate trisodium salt Chemical Structure
 BCP42041 2-Methylthioadenosine diphosphate trisodium salt 475193-31-8
2-Methylthioadenosine diphosphate trisodium salt is a potent purinergic agonist displaying selectivity for P2Y1, P2Y12 and P2Y13 receptors (pEC50 = 8.29 and 9.05 for P2Y1 and P2Y12, EC50 = 19 nM for P2Y13).
2-MeS-ADP Chemical Structure
 BCP42040 2-MeS-ADP 34983-48-7
2-MeS-ADP is an agonist of P2Y1, P2Y12 and P2Y13 receptors.
MRS 2179 tetrasodium salt Chemical Structure
 BCP40607 MRS 2179 tetrasodium salt 1454889-37-2
MRS-2179 tetrasodium salt is a competitive antagonist at P2Y1 receptors that inhibits the upregulation of NTPDase1 by ATPγS.
PSB12062 Chemical Structure
 BCP40451 PSB12062 55476-47-6
PSB-12062 is a potent and selective P2X4 antagonist with an IC50 of 1.38 μM for human P2X4.
Uridine 5'-diphosphoglucose disodium salt Chemical Structure
 BCP37401 Uridine 5'-diphosphoglucose disodium salt 28053-08-9
Uridine 5′-diphosphoglucose disodium salt is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms.
BAY-1797 Chemical Structure
 BCP36916 BAY-1797 2055602-83-8
BAY-1797 is a potent, orally active, and selective P2X4 antagonist, with an IC50 of 211 nM against human P2X4. BAY-1797 displays no or very weak activity on the other P2X ion channels. BAY-1797 shows anti-nociceptive and anti-inflammatory effects.
A 438079 Hydrochloride Chemical Structure
 BCP34027 A 438079 Hydrochloride 899507-36-9
A 438079 is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9.
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