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Nature products
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Raw Materials
Pim
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP13641 | LGB321 New | 1210415-88-5 |
LGB-321 is a potent and selective ATP-competitive small molecule inhibitor of PIM kinases (Pan-PIM kinase inhibitor).
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BCP30070 | TP-3654 New | 1361951-15-6 |
TP-3654 is a second-generation Pim kinase inhibitor with Ki values of 5 and 42 nM for Pim-1 and Pim-3, respectively.
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BCP24206 | LGH447 Hydrochloride | 1210416-52-6 |
LGH447 Hydrochloride is Potent and specific pan-PIM inhibitor, inhibiting proliferation of several AML cell lines, showing dual antitumoral and bone antiresorptive effects.
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BCP25255 | M-110 | 1395048-49-3 |
M-110 is a novel and highly selective inhibitor of PIM kinases; inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 uM, with no activity on normal human peripheral blood mononuclear cells up to 40 uM.
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BCP20644 | SMI-16a | 587852-28-6 |
Novel potent, cell-permeable, ATP-competitive inhibitor of Pim-1/2 kinases (IC50 = 150 nM and 20 nM against Pim-1 and Pim-2, respectively)
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BCP19936 | PIM447 | 1210608-43-7 |
PIM447 is novel pan-PIM kinase inhibitor, including Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase.
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BCP08968 | AZD-1208 | 1204144-28-4 |
AZD1208 is orally available, small molecule inhibitor of PIM kinases with potential antineoplastic activity.
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BCP19056 | CX 6258 hydrochloride hydrate | 1353858-99-7 |
CX-6258 hydrochloride hydrate is a potent, orally efficacious Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor with excellent biochemical potency and kinase selectivity.
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BCP06044 | SMI-4a | 438190-29-5; 327033-36-3 |
Selective, ATP-competitive Pim kinase inhibitor (IC50 values are 24 and 100 nM for Pim-1 and Pim-2 respectively). Displays selectivity over a panel of ~50 other kinases tested. Exhibits cytotoxicity in PC3 prostate carcinoma cells in vitro (IC50 = 17 μM).
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BCP07985 | CX-6258 | 1202916-90-2 |
CX-6258 is a potent, orally efficacious pan-Pim kinases Inhibitor with excellent biochemical potency and kinase selectivity.
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