Home   >  
Angiogenesis/Protein Tyrosine Kinase
  >  
TAM Receptor

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

TAM Receptor

Chemical Structure Cat. No. Product Name CAS No.
RU-301 Chemical Structure
BCP35046 RU-301 1110873-99-8
RU-301 is a novel pan-tam inhibitor, blocking the interface between tam ig1 ectodomain and gas6 lg domain, potently inhibiting axl reporter cell lines and native tam receptors cancer cell lines.
TAM-IN-2 Chemical Structure
BCP34892 TAM-IN-2 2135642-56-5
TAM-IN-2 is a TAM inhibitor extracted from patent US 20170275290 A1, pyrrolotriazine compound 0904.
UNC2541 Chemical Structure
BCP33929 UNC2541 1612782-86-1
UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor, binds in the MerTK ATP pocket, with an IC50 of 4.4 nM, more selective over Axl, Tyro3 and Flt3. UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM).
ONO7475 Chemical Structure
BCP33232 ONO7475 1646839-59-9
ONO-7475 is a potent and orally active Axl/Mer inhibitor. ONO-7475 targets and binds to both Axl and Mer, and prevents their activity.
BMS 777607 Chemical Structure
BCP13190 BMS 777607 1196681-44-3
BMS 777607 is a novel, selective and orally available ATP-competitive MET kinase inhibitor that primarily targets several MET family members, including RON, MET, Tyro-3 and AxI, with half maximal inhibitory concentration IC50 of 1.8 nmol/L, 3.9 nmol/L, 4.3 nmol/L and 1.1 nmol/L respectively.
S49076 HCl Chemical Structure
BCP29576 S49076 HCl 1265966-31-1
S49076 is an effective inhibitor of MET, AXL/MER, and FGFR1/2/3. S49076 potently blocked cellular phosphorylation of MET, AXL, and FGFRs and inhibited downstream signaling in vitro and in vivo.
UNC1062 Chemical Structure
BCP27888 UNC1062 1350549-36-8
UNC1062 is a novel MERTK-selective tyrosine kinase inhibitor
UNC569 Chemical Structure
BCP27883 UNC569 1350547-65-7
UNC569 is a novel small-molecule MER inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo.
UNC2025 Chemical Structure
BCP16544 UNC2025 1429881-91-3
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.
Sitravatinib Chemical Structure
BCP29099 Sitravatinib 1123837-84-2
Sitravatinib (MGCD516,MG-516) is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Kit, PDGFRβ, PDGFRα, c-Met, and Axl.
123下一页共 25 条记录 1 / 3 页 
0086-15971444841