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TAM Receptor

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TAM Receptor

Chemical Structure Cat. No. Product Name CAS No.
S49076 HCl Chemical Structure
BCP29576 S49076 HCl 1265966-31-1
S49076 is an effective inhibitor of MET, AXL/MER, and FGFR1/2/3. S49076 potently blocked cellular phosphorylation of MET, AXL, and FGFRs and inhibited downstream signaling in vitro and in vivo.
UNC1062 Chemical Structure
BCP27888 UNC1062 1350549-36-8
UNC1062 is a novel MERTK-selective tyrosine kinase inhibitor
UNC569 Chemical Structure
BCP27883 UNC569 1350547-65-7
UNC569 is a novel small-molecule MER inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo.
UNC2025 Chemical Structure
BCP16544 UNC2025 1429881-91-3
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.
Sitravatinib Chemical Structure
BCP29099 Sitravatinib 1123837-84-2
Sitravatinib (MGCD516,MG-516) is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Kit, PDGFRβ, PDGFRα, c-Met, and Axl.
S49076 Chemical Structure
BCP23760 S49076 1265965-22-7
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 values below 20 nM.
2-D08 Chemical Structure
BCP18314 2-D08 144707-18-6
2-D08 is a cell permeable, mechanistically unique inhibitor of protein sumoylation.
UNC2881 Chemical Structure
BCP12436 UNC2881 1493764-08-1
UNC2881 inhibits Mer kinase activity in 697 B-ALL cells with IC50 of 22 nM, and inhibits collagen-stimulated platelet aggregation.
NPS-1034 Chemical Structure
BCP15998 NPS-1034 1221713-92-3
NPS-1034 is a dual inhibitor of AXL and MET with IC50s of 10.3 and 48 nM, respectively.
Glesatinib hydrochloride Chemical Structure
BCP18872 Glesatinib hydrochloride 1123838-51-6
Glesatinib hydrochloride is an inhibitor of the MET and Axl receptor tyrosine kinase pathways, which drive tumour growth when altered.
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