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ROCK

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ROCK

Chemical Structure Cat. No. Product Name CAS No.
Ripasudil Hydrochloride Chemical Structure
BCP24238 Ripasudil Hydrochloride 223644-02-8
Ripasudil (K-115) hydrochloride dihydrate is potent ROCK inhibitor with IC50 of 51 nM and 19 nM for ROCK1 and ROCK2, respectively.
GSK269962 Chemical Structure
BCP27824 GSK269962 850664-21-0
GSK269962 is a selective ROCK inhibitor with IC50 values of 1.6 and 6 nM for ROCK-I and ROCK-II, respectively. GSK269962 can become an alternative worth considering in OAB treatment.
Glycyl-H 1152 dihydrochloride Chemical Structure
BCP27782 Glycyl-H 1152 dihydrochloride 913844-45-8
Glycyl-H 1152 dihydrochloride is a glycyl analog of the Rho-kinase inhibitor H 1152 dihydrochloride with an improved selectivity for ROCKII (IC50 = 0.0118, 2.35, 2.57, 3.26, > 10 and >10 μM for ROCKII, Aurora A, CAMKII, PKG, PKA and PKC, respectively).
GSK 269962 trihydrochloride Chemical Structure
BCP26170 GSK 269962 trihydrochloride 925213-80-5
GSK269962 is a selective ROCK inhibitor with IC50 values of 1.6 and 6 nM for ROCK-I and ROCK-II, respectively.
GSK269962 hydrochloride Chemical Structure
BCP26171 GSK269962 hydrochloride 2095432-71-4
GSK269962 is a selective ROCK inhibitor with IC50 values of 1.6 and 6 nM for ROCK-I and ROCK-II, respectively.
Fasudil hydrochloride hydrate Chemical Structure
BCP30939 Fasudil hydrochloride hydrate 186694-02-0
Fasudil, a potent inhibitor of ROCK with a Ki of 0.33 μM for ROCK1, which is also a potent Ca 2+ channel antagonist and vasodilator.
Y 39983 dihydrochloride Chemical Structure
BCP18325 Y 39983 dihydrochloride 173897-44-4
Y-33075 dihydrochloride is a selective ROCK inhibitor derived from Y-27632, and is more potent than Y-27632, with an IC50 of 3.6 nM.
Fasudil Chemical Structure
BCP26821 Fasudil 103745-39-7
Fasudil, a Rho-kinase inhibitor, has been shown to reduce portal venous pressure in cirrhotic rats.
Fasudil hydrochloride Chemical Structure
BCP26351 Fasudil hydrochloride 105628-07-7
Fasudil Hydrochloride is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Kis of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
BDP5290 Chemical Structure
BCP29732 BDP5290 1817698-21-7
BDP5290 is a potent inhibitor of both ROCK and MRCK with IC50s of 5 nM, 50 nM, 10 nM and 100 nM for ROCK1, ROCK2, MRCKα and MRCKβ, respectively.
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