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Potassium Channel

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Potassium Channel

Chemical Structure Cat. No. Product Name CAS No.
MCHr1 antagonist 2 Chemical Structure
BCP33948 MCHr1 antagonist 2 863115-70-2
MCH-R1 antagonist 22 is a novel potent antagonist of melanin concentrating hormone receptor 1 (MCH-R1).
Sematilide hydrochloride Chemical Structure
BCP25510 Sematilide hydrochloride 101526-62-9
Sematilide hydrochloride is a selective IKr channel blocker. Sematilide causes a concentration-dependent inhibition of the delayed rectifier K+ current (IC50=25 μM). Sematilide is a class III antiarrhythmic agent.
VU0134992 Chemical Structure
BCP33228 VU0134992 755002-90-5
VU0134992 is a selective Kir4.1 potassium channel pore blocker.
VU 590 dihydrochloride Chemical Structure
BCP33112 VU 590 dihydrochloride 313505-85-0
VU 590 dihydrochloride inhibits the renal outer medullary potassium channel (Kir1.1, ROMK) (IC50 = 294 nM).
QO-40 Chemical Structure
BCP33055 QO-40 1259536-70-3
QO-40 is an activator of KCNQ2/3 potassium channels.
KB-130015 Chemical Structure
BCP33047 KB-130015 147030-48-6
KB-130015 is a novel activator of hERG1 potassium channels, blocking native and recombinant hERG1 channels at high voltages.
NS19504 Chemical Structure
BCP33054 NS19504 327062-46-4
NS19504 is a Ca2+-activated K+ channel (BK channel, KCa1.1 channel) activator (EC50=11.0 µM) with relaxing effect on bladder smooth muscle spontaneous phasic contractions.
NS-5806 Chemical Structure
BCP33045 NS-5806 426834-69-7
NS-5806 is a KV4.3 channel activator. It acts by mediating the transient outward K+ current (Ito) and increasing IKv4.3 peak current amplitude in CHO-K1 cells expressing KV4.3 and KChIP2.
ICA-27243 Chemical Structure
BCP32732 ICA-27243 325457-89-4
ICA-27243 is a novel, potent and selective activator of M-current and KCNQ2/Q3 channels. ICA-27243 enhances KCNQ channel activation by shifting channel opening to more hyperpolarized potentials.
ICA-110381 Chemical Structure
BCP32590 ICA-110381 325457-99-6
ICA-110381 is a KV7.2/7.3 activator with EC50 of 0.38 uM.
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