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Ion Channel/Membrane Transporter
Potassium Channel

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Potassium Channel

Chemical Structure Cat. No. Product Name CAS No.
Glibornuride Chemical Structure
BCP13008 Glibornuride 26944-48-9
Glibornuride is a blocker of adenosine 5'-triphosphate (ATP)-sensitive K+ channels (KATP channels).
Halofantrine Chemical Structure
BCP13777 Halofantrine 69756-53-2
Halofantrine has been shown to preferentially block open and inactivated HERG channels leading to some degree of cardiotoxicity.
Glybenclamide Chemical Structure
BCP05327 Glybenclamide 10238-21-8
Glibenclamide is a sulfonylurea compound that modulates insulin production.
ML297 Chemical Structure
BCP29877 ML297 1443246-62-5
ML297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively).
Nigericin Chemical Structure
BCP13661 Nigericin 28380-24-7
Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus that works by acting as an H+, K+, and Pb2+ ionophore.
NS11021 Chemical Structure
BCP16316 NS11021 956014-19-0
NS 11021 is an activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1).
Vemakalant Chemical Structure
BCP15455 Vemakalant 794466-70-9
Vernakalant (RSD-1235) is an investigational mixed ion channel blocker that can terminate acute atrial fibrillation (AF) in humans at 2 to 5 mg/kg and may be more atrial-selective than available agents; in treatment of antiarrhythmic.
N-Acetylprocainamide hydrochloride Chemical Structure
BCP20733 N-Acetylprocainamide hydrochloride 34118-92-8
N-Acetylprocainamide is a class III antiarrhythmic, which blocks K+ channels.
N-acetylprocainamide (NAPA) was used as a model drug in the study of establishing a quantitative approach to predict the renal clearances of basic drugs using N-1-methylnicotinamide.
CLP-290 Chemical Structure
BCP25040 CLP-290 1181083-81-7
CLP-290 is a novel KCC2 modulator and prodrug of CLP-257, highly selective for KCC2 over related Cl- transporters.
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