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Apoptosis Pathway

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Chemical Structure Cat. No. Product Name CAS No.
Erastin Chemical Structure
BCP27907 Erastin 571203-78-6
Erastin is a ferroptosis activator.
RSL3 Chemical Structure
BCP18763 RSL3 1219810-16-8
RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS. RSL3 binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis.
FIN-56 Chemical Structure
BCP29145 FIN-56 1083162-61-1
FIN-56 is a specific inducer of ferroptosis.
Liproxstatin-1 Chemical Structure
BCP15985 Liproxstatin-1 950455-15-9
Liproxstatin-1 is a potent ferroptosis inhibitor in cells, in Gpx4(-/-) mice, and in a pre-clinical model of ischaemia/reperfusion-induced hepatic damage.
Ferrostatin-1 Chemical Structure
BCP17366 Ferrostatin-1 347174-05-4
Ferrostatin-1 is a potent inhibitor of ferroptosis with an EC50 of 60 nM.
CIL56 Chemical Structure
BCP29111 CIL56 300802-28-2
CIL56 is a YAP1 inhibitor. It acts by inducing non-apoptotic cell death, triggering cell death dependent upon the rate-limiting de novo lipid synthetic enzyme ACACA.