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Ferroptosis

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Ferroptosis

Chemical Structure Cat. No. Product Name CAS No.
UAMC3203 3HCl Chemical Structure
BCP30685 UAMC3203 3HCl UAMC32033HCl
UAMC-3203 is a novel potent, drug-like ferroptosis inhibitor with IC50 of 12 nM, inhibit erastin-induced ferroptotic cell death more potently than Ferrostatin-1; shows an improved protection compared to Fer-1 against multi-organ injury in mice, represents novel lead compounds with therapeutic potential in relevant ferroptosis-driven disease models.
UAMC-3203 Chemical Structure
BCP30684 UAMC-3203 2271358-64-4
UAMC-3203 is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.
Erastin Chemical Structure
BCP27907 Erastin 571203-78-6
Erastin is a ferroptosis activator.
RSL3 Chemical Structure
BCP18763 RSL3 1219810-16-8
RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS. RSL3 binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis.
FIN-56 Chemical Structure
BCP29145 FIN-56 1083162-61-1
FIN-56 is a specific inducer of ferroptosis.
Liproxstatin-1 Chemical Structure
BCP15985 Liproxstatin-1 950455-15-9
Liproxstatin-1 is a potent ferroptosis inhibitor in cells, in Gpx4(-/-) mice, and in a pre-clinical model of ischaemia/reperfusion-induced hepatic damage.
Ferrostatin-1 Chemical Structure
BCP17366 Ferrostatin-1 347174-05-4
Ferrostatin-1 is a potent inhibitor of ferroptosis with an EC50 of 60 nM.
CIL56 Chemical Structure
BCP29111 CIL56 300802-28-2
CIL56 is a YAP1 inhibitor. It acts by inducing non-apoptotic cell death, triggering cell death dependent upon the rate-limiting de novo lipid synthetic enzyme ACACA.
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