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Ferroptosis

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Ferroptosis

Chemical Structure Cat. No. Product Name CAS No.
Donafenib Chemical Structure
BCP34023 Donafenib 1130115-44-4
Donafenib is an oral multikinase inhibitor that targets Raf kinase and receptor tyrosine kinases with potential anticancer acivity. Donafenib is under clinical trials in China in patients with advanced hepatocellular carcinoma (HCC).
Imidazole ketone erastin Chemical Structure
BCP31858 Imidazole ketone erastin 1801530-11-9
Imidazole ketone erastin (IKE), is a potent, metabolically stable inhibitor of system xc- and inducer of ferroptosis potentially suitable for in vivo applications.
UAMC-3203 hydrochloride Chemical Structure
BCP30942 UAMC-3203 hydrochloride 2271358-65-5
UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.
Tinoridine Chemical Structure
BCP12825 Tinoridine 24237-54-5
Tinoridine, also known as Y-3642, is a non-steroidal anti-inflammatory drug.
Tinoridine hydrochloride Chemical Structure
BCP30905 Tinoridine hydrochloride 25913-34-2
Tinoridine hydrochloride is a nonsteroidal anti-inflammatory drug and also has potent radical scavenger and antiperoxidative activity.
PF-06282999 Chemical Structure
BCP20203 PF-06282999 1435467-37-0
PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potential useful for the treatment of cardiovascular diseases.
Verdiperstat Chemical Structure
BCP30847 Verdiperstat 890655-80-8
Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.
UAMC3203 3HCl Chemical Structure
BCP30685 UAMC3203 3HCl UAMC32033HCl
UAMC-3203 is a novel potent, drug-like ferroptosis inhibitor with IC50 of 12 nM, inhibit erastin-induced ferroptotic cell death more potently than Ferrostatin-1; shows an improved protection compared to Fer-1 against multi-organ injury in mice, represents novel lead compounds with therapeutic potential in relevant ferroptosis-driven disease models.
UAMC-3203 Chemical Structure
BCP30684 UAMC-3203 2271358-64-4
UAMC-3203 is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.
Erastin Chemical Structure
BCP27907 Erastin 571203-78-6
Erastin is a ferroptosis activator.
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