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DDR

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DDR

Chemical Structure Cat. No. Product Name CAS No.
DDR1-IN-2 Chemical Structure
BCP43189 DDR1-IN-2 1429617-90-2
DDR1-IN-2 is a potent, selective, ATP-competitive, orally available Discoidin domain receptor 1 (DDR1) inhibitor with IC50 of 6.8 nM in cell-free kinase assays.
DDR1-IN-1 Chemical Structure
BCP10994 DDR1-IN-1 1449685-96-4
DDR1-IN-1 is a potent and selective DDR1 receptor tyrosine kinase inhibitor with IC50/EC50 of 105 nM/87 nM; 4-fold less potent for DDR2 (IC50= 413 nM).
Sitravatinib Chemical Structure
BCP29099 Sitravatinib 1123837-84-2
Sitravatinib (MGCD516,MG-516) is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Kit, PDGFRβ, PDGFRα, c-Met, and Axl.
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