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Chemical Structure Cat. No. Product Name CAS No.
MK8745 Chemical Structure
BCP32607 MK8745 885325-71-3
MK-8745 is an aurora A kinase inhibitor with an IC50 of 0.6 nM.
CXD101 Chemical Structure
BCP24800 CXD101 934828-12-3
CXD101 is a potent, selective and orally active class I HDAC inhibitor with IC50s of 63 nM, 570 nM and 550 nM for HDAC1, HDAC2 and HDAC3, respectively. CXD101 has no activity against HDAC class II. CXD101 has antitumor activity.
FM-479 Chemical Structure
BCP32593 FM-479 2226521-64-6
FM-479 is a negative control for FM-381 (GLXC-09922).
TCJL37 Chemical Structure
BCP32555 TCJL37 1258294-34-6
TCJL-37 is a potent TYK2 inhibitor.
PF-06409577 Chemical Structure
BCP32554 PF-06409577 1467057-23-3
PF-06409577 is a potent and selective allosteric activator of AMPK α1β1γ1 isoform with an EC50 of 7 nM.
dBET57 Chemical Structure
BCP32540 dBET57 1883863-52-2
dBET57 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC) which exhibits significant and selective degradation of BRD4 BD1 but is inactive on BRD4 BD2.
(R)-JQ-1 (carboxylic acid) Chemical Structure
BCP32538 (R)-JQ-1 (carboxylic acid) 202592-24-3
JQ1 Carboxylic Acid, also known as JQ1 Acid, is an inhibitor of bromodomain and extra terminal domain (BET) family proteins.
4alpha-PDD Chemical Structure
BCP32104 4alpha-PDD 27536-56-7
4alpha-PDD is a negative control for Phorbol-12,13-didecanoate (PDD) and Phorbol-12-myristate-13-acetate (PMA). Though it is inactive for signaling through PKC, 4alpha-PDD has been shown to activate transient receptor potential vanilloid 4 (TRPV4) channels.
QCA570 Chemical Structure
BCP32101 QCA570 2207569-08-0
QCA570 is a potent BET degrader based on PROTAC, with an IC50 of 10 nM for BRD4 BD1 Protein.
GSK621 Chemical Structure
BCP31970 GSK621 1346607-05-3
GSK621 is a specific and potent AMPK activator.
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