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Angiogenesis/Protein Tyrosine Kinase
c Met

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c Met

Chemical Structure Cat. No. Product Name CAS No.
JNJ-38877605 Chemical Structure
BCP44121 JNJ-38877605 943540-74-7
JNJ-38877618 is a hepatocyte growth factor receptor (HGFR; MET; c-Met) inhibitor potentially for the treatment of solid tumours.
Norleual Chemical Structure
BCP41927 Norleual 334994-34-2
Norleual, an angiotensin IV analog, competitively inhibited the binding of HGF to its receptor c-Met in mouse liver membranes. It is also an AT4 receptor antagonist, which disrupts LTP stabilization.
PF-04217903 phenolsulfonate Chemical Structure
BCP36115 PF-04217903 phenolsulfonate 1159490-85-3
PF-04217903 phenolsulfonate is a potent ATP-competitive c-Met kinase inhibitor. It shows more than 1,000-fold selectivity relative to 208 kinases.PF-04217903 is a potent ATP-competitive c-Met kinase inhibitor with Ki of 4.8 nM for human c-Met.
ARQ 197 Chemical Structure
BCP28549 ARQ 197 1000873-98-2
ARQ-197 is a selective inhibitor of the c-Met receptor tyrosine kinase
S49076 HCl Chemical Structure
BCP35053 S49076 HCl 1265965-19-2
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 values below 20 nM.
Bozitinib Chemical Structure
BCP34901 Bozitinib 1440964-89-5
Bozitinib (PLB-1001) is a highly selective c-MET kinase inhibitor with blood-brain barrier permeability.
TAS-115 mesylate Chemical Structure
BCP34015 TAS-115 mesylate 1688673-09-7
TAS-115 mesylate is a potent VEGFRand hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase inhibitor, with IC50s of 30 and 32 nM for rVEGFR2 and rMET, respectively.
TAS-115 Chemical Structure
BCP34014 TAS-115 1190836-34-0
TAS-115 is a potent VEGFR and hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase inhibitor with IC50s of 30 and 32 nM for rVEGFR2 and rMET, respectively.
Glumetinib Chemical Structure
BCP31155 Glumetinib 1642581-63-2
Glumetinib is a potent and highly selective c-Met kinase inhibitor with an IC50 of 0.42 nM. Glumetinib shows antitumor activity and a superior safety margin.
AMG51 Chemical Structure
BCP21618 AMG51 890019-63-3
AMG-51 is a selective inhibitor of c-Met kinase
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