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Chemical Structure Cat. No. Product Name CAS No.
CAY10602 Chemical Structure
 BCP32626 CAY10602 374922-43-7
CAY10602 is a SIRT1 activator.
PNU112455A hydrochloride Chemical Structure
 BCP32610 PNU112455A hydrochloride 21886-12-4
PNU112455A is an ATP site competetive inhibitor of CDK2 and CDK5.
Longdaysin Chemical Structure
 BCP32583 Longdaysin 1353867-91-0
Longdaysin is a novel inhibitor of CK1, ERK2, and CDK7 kinases.
MK8745 Chemical Structure
 BCP32607 MK8745 885325-71-3
MK-8745 is an aurora A kinase inhibitor with an IC50 of 0.6 nM.
CXD101 Chemical Structure
 BCP24800 CXD101 934828-12-3
CXD101 is a potent, selective and orally active class I HDAC inhibitor with IC50s of 63 nM, 570 nM and 550 nM for HDAC1, HDAC2 and HDAC3, respectively. CXD101 has no activity against HDAC class II. CXD101 has antitumor activity.
BioE-1115 Chemical Structure
 BCP32544 BioE-1115 1268863-35-9
BioE-1115 is a highly selective and potent PAS kinase (PASK) inhibitor with an IC50 of ~4 nM. BioE-1115 is also a potent casein kinase 2α inhibitor with an IC50 of ~10 μM.
CDK8/19-IN-1 Chemical Structure
 BCP23526 CDK8/19-IN-1 1818427-07-4
CDK8/19-IN-1 is a potent, selective and oral bioavailable CDK8/19 dual inhibitor, with IC50s of 0.46 nM, 0.99 nM and 270 nM for CDK8, CDK19 and CDK9, respectively.
Tesaglitazar Chemical Structure
 BCP23582 Tesaglitazar 251565-85-2
Tesaglitazar is a PPAR agonist potentially for the treatment of type 2 diabetes. The drug had completed several phase III clinical trials, however in May, 2006 AstraZeneca announced that it had discontinued further development.
SY-1365 Chemical Structure
 BCP28906 SY-1365 1816988-80-3
SY-1365 is a novel selective covalent inhibitor of cyclin-dependent kinase 7 (CDK7).
VXc-​486 Chemical Structure
 BCP20714 VXc-​486 1384984-18-2
VXc-486 is active against drug-resistant isolates, has bactericidal activity, and kills intracellular and dormant M. tuberculosis bacteria in a low-oxygen environment.
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