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Chemical Structure Cat. No. Product Name CAS No.
ABC-1183 Chemical Structure
BCP30547 ABC-1183 1042735-18-1
ABC-1183 is a selective dual GSK3α/β and CKD9 inhibitor.
Nedisertib Chemical Structure
BCP30542 Nedisertib 1637542-33-6
Nedisertib (M3814) is a potent and selective inhibitor of DNA-dependent Protein Kinase (DNA-PK), with an IC50 of <3 nM.
MK-0731 Chemical Structure
BCP30541 MK-0731 845256-65-7
MK-0731 is a synthetic small molecule with potential antineoplastic activity.
SEL120-34A Chemical Structure
BCP30533 SEL120-34A 1609522-33-9
SEL120-34A is a potent, selective, orally available, ATP-competitive CDK8 inhibitor, with IC50s of 4.4 nM and 10.4 nM for CDK8/CycC and CDK19/CycC, respectively, with antitumor activity.
Corin Chemical Structure
BCP30529 Corin 1808113-09-8
Corin is a dual inhibitor of histone lysine specific demethylase (LSD1) and histone deacetylase (HDAC), with a Ki(inact) of 110 nM for LSD1 and an IC50 of 147 nM for HDAC1.
BSJ-03-123 Chemical Structure
BCP30504 BSJ-03-123 BSJ-03-123
BSJ-03-123 is a potent and novel CDK6-selective small-molecule degrader (PROTAC).
dBET6 Chemical Structure
BCP30500 dBET6 1950634-92-0
dBET6 is a novel degrader of BET bromodomain proteins. dBET6 prompts a collapse of global elongation that phenocopies CDK9 inhibition.
Daunomycinone Chemical Structure
BCP07437 Daunomycinone 21794-55-8
Daunomycinone is the aglycone of daunomycin.
Tinostamustine hydrochloride Chemical Structure
BCP30456 Tinostamustine hydrochloride 1793059-58-1
Tinostamustine, also known as EDO-S101, is an alkylatlng histone-deacetylase inhibitor (HDACi) fusion molecule.
RK-287107 Chemical Structure
BCP30401 RK-287107 2171386-10-8
RK-287107 is a potent TNKS/TNKS2 inhibitor (IC50 = 14.4 nM) with >7000-fold selectivity against the PARP1 enzyme, which inhibits WNT-responsive TCF reporter activity and proliferation of human colorectal cancer cell line COLO-320DM.
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