Home   >  
∨

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

Cell Cycle/DNA Damage

Chemical Structure Cat. No. Product Name CAS No.
Zotatifin Chemical Structure
 BCP35487 Zotatifin 2098191-53-6
Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex. Zotatifin shows robust antiviral effects, it effectively reduces viral infectivity by inhibiting SARS-CoV-2 NP protein biogenesis (IC90=37 nM). Zotatifin induces cell apoptosis.
Prexasertib dimesylate Chemical Structure
 BCP35489 Prexasertib dimesylate 1234015-58-7
Prexasertib dimesylate (LY2606368 dimesylate) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of <1 nM.
GW6471 Chemical Structure
 BCP35208 GW6471 880635-03-0
GW 6471 is a potent PPARα antagonist.
CK1-IN-1 Chemical Structure
 BCP35045 CK1-IN-1 1784751-20-7
CK1-IN-1 is a casein kinase 1 (CK1) inhibitor extracted from patent WO2015119579A1, compound 1c, has IC50s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK, respectively.
beta-Boswellic Acid Chemical Structure
 BCP35037 beta-Boswellic Acid 631-69-6
beta-Boswellic Acid is a triterpenoid with anti-hyperlipidemic, anti-carcinogenic and anti-tumor activities.
D-scyllo-Inositol, 1-azido-1-deoxy-2,3,4,5,6-pentakis-O-(phenylmethyl)- Chemical Structure
 BCP34936 D-scyllo-Inositol, 1-azido-1-deoxy-2,3,4,5,6-pentakis-O-(phenylmethyl)- 868550-22-5
1-Amino-1-desoxy-scyllo-inosit Chemical Structure
 BCP34937 1-Amino-1-desoxy-scyllo-inosit 16051-25-5
Sarcolysin hydrochloride Chemical Structure
 BCP34935 Sarcolysin hydrochloride 1465-26-5
DL-Melphalan hydrochloride is a nitrogen mustard and alkylating agent that has been studied for use in multiple myeloma therapy.
LY518674 Chemical Structure
 BCP34904 LY518674 425671-29-0
LY518674 is a potent, selective PPARα antagonist, with an EC50 of 42 nM for human PPARα. LY518674 reduces triglycerides in and increased HDL-C and is used for the treatment of atherosclerosis.
(S)-Crizotinib Chemical Structure
 BCP34894 (S)-Crizotinib 1374356-45-2
(S)-Crizotinib is an MTH1 inhibitor. By inhibiting MTH1, (S)-Crizotinib disrupts nucleotide pool homeostasis, induces an increase in DNA single-strand breaks, activates DNA repair in human colon carcinoma cells, and effectively suppresses tumor growth in animal models.
123下一页末页共 958 条记录 1 / 96 页 
0086-15971444841