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Dopamine Receptor

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Dopamine Receptor

Chemical Structure Cat. No. Product Name CAS No.
NPD8733 Chemical Structure
 BCP38016 NPD8733 696655-62-6
NPD8733 is a small-molecule ligand of valosin-containing protein (VCP)/p97, binds to the D1 domain of VCP/p97.
OS-3-106 Chemical Structure
 BCP37979 OS-3-106 1580000-17-4
OS-3-106 is a novel dopamine D3 receptor-selective partial agonist.
Pramipexole Chemical Structure
 BCP37760 Pramipexole 104632-26-0
Pramipexole (Mirapex) is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.
Raclopride Chemical Structure
 BCP35657 Raclopride 84225-95-6
Raclopride is a dopamine D2/D3 receptor antagonist, which binds to D2 and D3 receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D1 and D4 receptors with Kis of 18000 nM and 2400 nM, respectively.
N-Methyldopamine hydrochloride Chemical Structure
 BCP35497 N-Methyldopamine hydrochloride 62-32-8
N-Methyldopamine hydrochloride is an andregenic and dopamine receptor agonist; active metabolite of Ibopramine.
ML417 Chemical Structure
 BCP35340 ML417 1386162-69-1
ML417 is a selective and brain penetrant D3 dopamine receptor (D3R) agonist, with an EC50 of 38 nM. ML417 potently promotes D3R-mediated β-arrestin translocation, G protein mediated signaling, and pERK phosphorylation with minimal effects on other GPCR-mediated signaling. ML417 exhibits neuroprotection against toxin-induced neurodegeneration of dopaminergic neurons.
Methylphenidate hydrochloride Chemical Structure
 BCP34044 Methylphenidate hydrochloride 298-59-9
Methylphenidate hydrochloride is an inhibitor of dopamine and noradrenalin transporters that increases the extracellular concentration of dopamine and noradrenalin.
ABT-724 trihydrochloride Chemical Structure
 BCP33286 ABT-724 trihydrochloride 587870-77-7
ABT 724 trihydrochloride is a potent dopamine D4 receptor partial agonist (EC50 = 12.4 nM; 61% efficacy vs. dopamine) for treatment of sexual dysfunction.
6-Hydroxydopamine hydrobromide Chemical Structure
 BCP25700 6-Hydroxydopamine hydrobromide 636-00-0
6-Hydroxydopamine hydrobromide is a neurotoxin. It acts by destroying catecholaminergic terminals.
Naxagolide hydrochloride Chemical Structure
 BCP25707 Naxagolide hydrochloride 99705-65-4
Naxagolide is a potent and selective dopamine D2 agonist.
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