Home   >  
Wnt/Stem Cell
  >  
Wnt

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

Wnt

Chemical Structure Cat. No. Product Name CAS No.
KY1220 Chemical Structure
BCP34008 KY1220 292168-79-7
KY1220 is a small molecule that simultaneously degrades β-catenin and Ras by inhibition of the Wnt/β-catenin pathway.
CHIR-99021 trihydrochloride Chemical Structure
BCP26069 CHIR-99021 trihydrochloride 1782235-14-6
CHIR99021 is an orally active and potent GSK3 inhibitor. CHIR-73911 exhibited GSK3 IC50 in the low nanomolar range and excellent selectivity. CHIR-73911 activates glycogen synthase in insulin receptorexpressing CHO-IR cells and primary rat hepatocyte
iCRT3 Chemical Structure
BCP32691 iCRT3 901751-47-1
iCRT3 is an inhibitor of both Wnt and β-catenin-responsive transcription.
QS11 Chemical Structure
BCP02472 QS11 944328-88-5
Additionally, Wnt Synergist, QS11 has been shown to work synergistically with Wnt-3a to specifically activate the Wnt/β-catenin signaling pathway in vitro. A Super(8X)TOPFlash reporter assay using HEK293 cells revealed increases in basal transcription activity by application of QS11 (2-fold), Wnt-3a (40-fold), and QS11/Wnt-3a (200-fold).
Adavivint Chemical Structure
BCP30409 Adavivint 1467093-03-3
Adavivint is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells.
KYA1797K Chemical Structure
BCP29963 KYA1797K 1956356-56-1
KYA1797K is a potent and selective Wnt/β-catenin inhibitor with an IC50 of 0.75 µM.
Gigantol Chemical Structure
BCP29252 Gigantol 67884-30-4
Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells.
MN 64 Chemical Structure
BCP16851 MN 64 92831-11-3
MN-64 is a inhibitor of tankyrases, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.
Triptonide Chemical Structure
BCP26007 Triptonide 38647-11-9
Triptonide(NSC 165677; PG 492), extracted from Tripterygium wilfordii Hook.
Cardiogenol C Chemical Structure
BCP16146 Cardiogenol C 671225-39-1
Cardiogenol C is a diaminopyrimidine compound that induces the differentiation of MHC- (myosin heavy chain) positive cardiomyocytes from embryonic stem cells with an EC50 value of 0.1 μM.
123下一页末页共 33 条记录 1 / 4 页 
0086-13720134139