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Wnt/Stem Cell

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Chemical Structure Cat. No. Product Name CAS No.
QS11 Chemical Structure
BCP02472 QS11 944328-88-5
Additionally, Wnt Synergist, QS11 has been shown to work synergistically with Wnt-3a to specifically activate the Wnt/β-catenin signaling pathway in vitro. A Super(8X)TOPFlash reporter assay using HEK293 cells revealed increases in basal transcription activity by application of QS11 (2-fold), Wnt-3a (40-fold), and QS11/Wnt-3a (200-fold).
Adavivint Chemical Structure
BCP30409 Adavivint 1467093-03-3
Adavivint is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells.
KYA1797K Chemical Structure
BCP29963 KYA1797K 1956356-56-1
KYA1797K is a potent and selective Wnt/β-catenin inhibitor with an IC50 of 0.75 µM.
Gigantol Chemical Structure
BCP29252 Gigantol 67884-30-4
Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells.
MN 64 Chemical Structure
BCP16851 MN 64 92831-11-3
MN-64 is a inhibitor of tankyrases, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.
Triptonide Chemical Structure
BCP26007 Triptonide 38647-11-9
Triptonide(NSC 165677; PG 492), extracted from Tripterygium wilfordii Hook.
Cardiogenol C Chemical Structure
BCP16146 Cardiogenol C 671225-39-1
Cardiogenol C is a diaminopyrimidine compound that induces the differentiation of MHC- (myosin heavy chain) positive cardiomyocytes from embryonic stem cells with an EC50 value of 0.1 μM.
Cardiogenol C, Hydrochloride Chemical Structure
BCP26174 Cardiogenol C, Hydrochloride 1049741-55-0
Cardiogenol C hydrochloride is a potent and cell permeable inducer of embryonic stem cell differentiation in cardiomyocytes displaying an Ec50 of 100nm.
IQ-1 Chemical Structure
BCP19305 IQ-1 331001-62-8
IQ-1 has many functions such as decreasing Wnt-stimulated phosphorylation, maintaining the pluripotency of murine ESCs, preventing PP2A/Nkd interaction and so on.
KY02111 Chemical Structure
BCP07010 KY02111 1118807-13-8
Promotes differentiation of human ESCs and iPSCs into cardiomyocytes.
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