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SCD

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SCD

Chemical Structure Cat. No. Product Name CAS No.
PluriSln 1 Chemical Structure
BCP07902 PluriSln 1 91396-88-2
PluriSln 1 is an inhibitor of stearoyl-coA desaturase (SCD1), the key enzyme in oleic acid biosynthesis, revealing a unique role for lipid metabolism in hPSCs.
Aramchol Chemical Structure
BCP19722 Aramchol 246529-22-6
Aramchol is a cholesterol solubilizer that prevents gallstone formation in inbred mice. Aramchol reduces liver fat content in patients with nonalcoholic fatty liver disease.
CVT-12012 Chemical Structure
BCP30029 CVT-12012 1018675-35-8
CVT-12012 is a bio-active chemical compound and is highly potent in a human cell-based (HEPG2) SCD assay with IC50 value of 6nM.
SCD1 inhibitor Chemical Structure
BCP25220 SCD1 inhibitor 1231243-91-6
SCD1 inhibitor is a novel stearoyl-CoA desaturase1 (SCD1) inhibitor.The compound exhibited robust in vivo activity with dose-dependent desaturation index lowering effects.
MK-8245 Chemical Structure
BCP06568 MK-8245 1030612-87-3
MK-8245 is a liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy.
MK8245 Chemical Structure
BCP02516 MK8245 1030612-90-8
MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy.
MK-8245 Trifluoroacetate Chemical Structure
BCP17297 MK-8245 Trifluoroacetate 1415559-41-9
MK-8245 trifluoroacetate is a liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy.
GSK1940029 Chemical Structure
BCP23649 GSK1940029 1150701-66-8
GSK1940029 is a stearoyl-coa desaturase (SCD) extracted from patent WO/2009060053 A1, compound example 16.
A939572 Chemical Structure
BCP27670 A939572 1032229-33-6
A939572 is a potent, and orally bioavailable SCD1 inhibitor with IC50 values of <4 nM and 37 nM for mSCD1 and hSCD1, respectively.
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