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FTase

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FTase

Chemical Structure Cat. No. Product Name CAS No.
LB42708 Chemical Structure
BCP09683 LB42708 226929-39-1
LB42708 is an orally active farnesyltransferase (FTase) inhibitor with IC50 of 0.8, 1.2, and 2.0 nM toward H-ras, N-ras, and K-ras, respectively.
BMS-214662 hydrochloride Chemical Structure
BCP19824 BMS-214662 hydrochloride 195981-08-9
BMS-214662 is a potent and selective farnesyl transferase inhibitor with potent antitumor activity with an IC50 of 1.35 nM.
Lonafarnib Chemical Structure
BCP07027 Lonafarnib 193275-84-2
Lonafarnib is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.
L778123 analog Chemical Structure
BCP16388 L778123 analog 197853-31-9
L778123 hydrochloride Chemical Structure
BCP17750 L778123 hydrochloride 253863-00-2
L-778123 hydrochloride is an inhibitor of FPTase and GGPTase-I with IC50 of 2 nM and 98 nM in enzyme inhibition determination.
Tipifarnib Chemical Structure
BCP02262 Tipifarnib 192185-72-1
Tipifarnib is a potent and specific farnesyltransferase inhibitor with an IC50 of 0.6 nM.
Tipifarnib S enantioMer Chemical Structure
BCP29288 Tipifarnib S enantioMer 192185-71-0
Tipifarnib S enantiomer is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM. Tipifarnib S enantiomer is the less active isomer.
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