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MNK

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MNK

Chemical Structure Cat. No. Product Name CAS No.
EFT-508 Chemical Structure
BCP18993 EFT-508 1849590-01-7
eFT508 is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of 1-2 nM.
SLV-2436 Chemical Structure
BCP29427 SLV-2436 2095704-43-9
SLV-2436 is a highly potent and ATP-competitive inhibitor of MNK1 and MNK2 with IC50s of 10.8  nM and 5.4 nM, respectively.
CGP 57380 Chemical Structure
BCP27993 CGP 57380 522629-08-9
CGP 57380 is a cell-permeable pyrazolo-pyrimidine compound that acts as a selective inhibitor of Mnk1 with IC50 of 2.2 μM, but has no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases.
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