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HCV Protease

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HCV Protease

Chemical Structure Cat. No. Product Name CAS No.
Beclabuvir Chemical Structure
 BCP11013 Beclabuvir 958002-33-0
Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM.
MK-4882 Chemical Structure
 BCP13058 MK-4882 1246472-08-1
MK-4882 is a potent HCV NS5A inhibitor.
Elbasvir Chemical Structure
 BCP29961 Elbasvir 1370468-36-2
Elbasvir (MK-8742) is a hepatitis C virus nonstructural protein 5A (HCV NS5A) inhibitor with EC50s of 4, 3 and 3 nM against genotype 1a, 1b, and 2a, respectively.
Faldaprevir Chemical Structure
 BCP27809 Faldaprevir 801283-95-4
Faldaprevir, also known as BI-201335, is a potent NS3/NS4A protease inhibitor potentially for the treatment of HCV infection.
Sovaprevir Chemical Structure
 BCP28074 Sovaprevir 1001667-23-7
Sovaprevir is a nonstructural 3 (NS3) protease inhibitor potentially for the treatment of HCV infection
MK-5172 Chemical Structure
 BCP28567 MK-5172 1350514-68-9
MK-5172 is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively.
Ombitasvir Chemical Structure
 BCP28363 Ombitasvir 1258226-87-7
Ombitasvir is a potent inhibitor of the hepatitis C virus protein NS5A, with EC50s of 0.82 to 19.3 pM against HCV genotypes 1 to 5 and 366 pM against genotype 6a.
Ravidasvir dihydrochloride Chemical Structure
 BCP20103 Ravidasvir dihydrochloride 1303533-81-4
Ravidasvir, also known as PPI-668 and ASC16, is a second-generation, orally active, potent and selective HCV NS5A protein inhibitor.
Ravidasvir Chemical Structure
 BCP20102 Ravidasvir 1242087-93-9
Ravidasvir (PPI-668) is an investigational NS5A inhibitor in clinical trials for chronic hepatitis C genotype 4.
Ledipasvir (acetone) Chemical Structure
 BCP24147 Ledipasvir (acetone) 1441674-54-9
Ledipasvir acetone is a hepatitis C virus (HCV) NS5A inhibitor.
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