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AMPK

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AMPK

Chemical Structure Cat. No. Product Name CAS No.
EX229 Chemical Structure
BCP29074 EX229 1219739-36-2
AMPK Activator 991 is a novel AMPK activator, increasing AMPK activity of both AMPKgamma1- and AMPKgamma3-containing complexes in mouse skeletal muscle.
XMD-17-51 Chemical Structure
BCP29865 XMD-17-51 1628614-50-5
XMD-17-51 is a potent and selective NUAK1 inhibitor.
Ginkgolide C Chemical Structure
BCP25993 Ginkgolide C 15291-76-6
Ginkgolide C is a flavone isolated from Ginkgo biloba leaves, possessing multiple biological functions, such as decreasing platelet aggregation and ameliorating Alzheimer disease.
MK-3903 Chemical Structure
BCP29075 MK-3903 1219737-12-8
MK-3903 is a potent and selective AMP-activated protein kinase (AMPK) activator with an EC50 of 8 nM.
O-304 Chemical Structure
BCP29039 O-304 1261289-04-6
O-304 is a small molecule AMPK activator and PCSK9 modulator.
Acadesine Chemical Structure
BCP06900 Acadesine 2627-69-2
AICAR is an activator of AMP-activated protein kinase (AMPK), down-regulates the insulin receptor expression in HepG2 cells.
BML-275 2HCl Chemical Structure
BCP06635 BML-275 2HCl 1219168-18-9
Dorsomorphin 2Hcl (Compound C; BML-275) has been shown to act as a potent and selective inhibitor of AMPK (AMP-activated protein kinase; Ki = 109 nM), induced by AICAR and metformin; also inhibits the bone morphogenetic protein type 1 receptors ACTR-I (ALK2), BMPR-IA (ALK3), and BMPR-IB (ALK 6).
6-Gingerol Chemical Structure
BCP13252 6-Gingerol 23513-14-6
6-Gingerol is an active compound isolated from Ginger (Zingiber officinale Rosc), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
HTH-01-015 Chemical Structure
BCP14400 HTH-01-015 1613724-42-7
HTH-01-015 is a potent and selective inhibitor of NUAK1 with IC50 of 100 nM, does not significantly inhibit NUAK2 (IC50 of >10 μM).
Bempedoic acid Chemical Structure
BCP16083 Bempedoic acid 738606-46-7
Bempedoic acid, also known as ESP-55016 and ETC-1002, is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies. Bempedoic acid is absorbed rapidly in the small intestine and enters the liver through cell surface receptors different from those transporters that selectively take up statins. Bempedoic acid is a regulator of lipid and carbohydrate metabolism.
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