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Chemical Structure Cat. No. Product Name CAS No.
OTS964 Chemical Structure
BCP28759 OTS964 1338545-07-5
OTS964 is a potent TOPK inhibitor with an IC50 value of 28 nM.
AstragalosideIV Chemical Structure
BCP28188 AstragalosideIV 84687-43-4
Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells.
TIC10 Analogue Chemical Structure
BCP20950 TIC10 Analogue 41276-02-2
TIC10 isomer is the isomer of TIC10. TIC10 isomer does not possess the reported biological activity of inducing TRIAL expression.
Honokiol Chemical Structure
BCP28282 Honokiol 35354-74-6
Honokiol is a hydroxylated biphenyl compound, which inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.
GDC-0623 Chemical Structure
BCP28689 GDC-0623 1168091-68-6
GDC-0623 is a potent, ATP-uncompetitive inhibitor of MEK1 (Ki=0.13 nM, +ATP), and displays 6-fold weaker potency against HCT116 (KRAS (G13D), EC50=42 nM) versus A375 (BRAFV600E, EC50=7 nM).
APS279 hydrochloride Chemical Structure
BCP23567 APS279 hydrochloride 2002381-31-7
APS-2-79 hydrochloride behaves as a kinase suppressor of Ras (KSR)-dependent antagonist of RAF-mediated MEK phosphorylation. APS-2-79 binds directly to KSR2 within the KSR2-MEK1 complex with an IC 50 of 120±23 nM for KSR2.
LY2584702 hydrochloride Chemical Structure
BCP15580 LY2584702 hydrochloride 1082948-81-9
LY-2584702 Hcl is an orally available inhibitor of p70S6K signaling; inhibits p70S6K and prevents phosphorylation of the S6 subunit of ribosomes.
Marimastat Chemical Structure
BCP10998 Marimastat 154039-60-8
Marimastat(BB 2516; TA2516) is a broad spectrum inhibitor of MMPs (IC50 values are 3, 5, 6, 9 and 13 nM for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7 respectively).
Alda-1 Chemical Structure
BCP17146 Alda-1 349438-38-6
Alda-1 is an ALDH2 agonist, cell-permeable activator of both the wild-type ALDH2*1 and the asian E487K mutant ALDH2*2 forms of mitochondrial aldehyde dehydrogenase 2 (mtALDH2).
LJH 685 Chemical Structure
BCP19686 LJH 685 1627710-50-2
LJH685 is a potent , specific and selective RSK inhibitor, inhibits RSK1, 2, and 3 biochemical activities with IC50 of 4 to 13 nM.
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